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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">46085</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2025-29-3-302-311</article-id><article-id pub-id-type="edn">ONQRTA</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ONCOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОНКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Multidisciplinarity and interdisciplinarity in medicine and education as a tool for improving the quality of patients’ antitumor treatment</article-title><trans-title-group xml:lang="ru"><trans-title>Мультидисциплинарность и междисциплинарность в медицине и образовании как инструмент повышения качества противоопухолевого лечения пациентов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4068-7698</contrib-id><contrib-id contrib-id-type="spin">7091-8276</contrib-id><name-alternatives><name xml:lang="en"><surname>Avanesov</surname><given-names>Anatoliy M.</given-names></name><name xml:lang="ru"><surname>Аванесов</surname><given-names>А. М.</given-names></name></name-alternatives><email>gvozdikova_en@pfur.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8037-594X</contrib-id><contrib-id contrib-id-type="spin">2562-4392</contrib-id><name-alternatives><name xml:lang="en"><surname>Titova</surname><given-names>Vera A.</given-names></name><name xml:lang="ru"><surname>Титова</surname><given-names>В. А.</given-names></name></name-alternatives><email>gvozdikova_en@pfur.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5426-1084</contrib-id><contrib-id contrib-id-type="spin">9410-6747</contrib-id><name-alternatives><name xml:lang="en"><surname>Gvozdikova</surname><given-names>Evgeniya N.</given-names></name><name xml:lang="ru"><surname>Гвоздикова</surname><given-names>Е. Н.</given-names></name></name-alternatives><email>gvozdikova_en@pfur.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">RUDN University</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Scientific Center of Roentgenoradiology</institution></aff><aff><institution xml:lang="ru">Российский научный центр рентгенрадиологии</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-09-25" publication-format="electronic"><day>25</day><month>09</month><year>2025</year></pub-date><volume>29</volume><issue>3</issue><issue-title xml:lang="en">ONCOLOGY</issue-title><issue-title xml:lang="ru">ОНКОЛОГИЯ</issue-title><fpage>302</fpage><lpage>311</lpage><history><date date-type="received" iso-8601-date="2025-09-25"><day>25</day><month>09</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Avanesov A.M., Titova V.A., Gvozdikova E.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Аванесов А.М., Титова В.А., Гвоздикова Е.Н.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Avanesov A.M., Titova V.A., Gvozdikova E.N.</copyright-holder><copyright-holder xml:lang="ru">Аванесов А.М., Титова В.А., Гвоздикова Е.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/46085">https://journals.rudn.ru/medicine/article/view/46085</self-uri><abstract xml:lang="en"><p>Relevance. Despite the advances in modern medicine, the improvement of treatment methods for many diseases, the overall incidence of cancer, as well as mortality from cancer, remains high. At the same time, the approaches to antitumor treatment themselves often significantly reduce the quality of life of patients, limit their ability to work, which causes certain social and economic damage from these diseases. In this regard, issues of improving the quality of antitumor treatment are among the priority issues in healthcare today. The purpose of this study is to find new possible tools and approaches to improve the quality of antitumor treatment for patients at different levels, including clinical and educational. It is possible to significantly change and improve the quality of oncological care for patients through the tools and technologies of accompanying therapy, including dental support, the clinical significance of which is critically underestimated today. Improving the methods of accompanying therapy is a multidisciplinary problem that can and should be solved exclusively in the context of interdisciplinary interaction of specialists of different profiles. Currently, the development of dental support is limited by a number of factors, such as clinical or organizational, but one of the most significant factors is the insufficient focus on this problem in medical education. Of course, the current pace of development of medicine, the introduction of new technologies, including artificial intelligence, increase the requirements for a modern specialist doctor and require extensive knowledge that goes beyond one discipline, including the presence of interdisciplinary thinking. Conclusion.Thus, the introduction of interdisciplinary approaches in the training of future dentists and doctors specializing in «General Medicine», training students at the intersection of different specialties (oncology and dentistry, dentistry and hematology) can improve the quality of dental support in particular, and the quality of antitumor treatment in general.</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность. Несмотря на успехи современной медицины, совершенствование методов лечения многих болезней, общая онкологическая заболеваемость, а также смертность от онкологии остается на высоком уровне. При этом сами подходы к противоопухолевому лечению часто существенно снижают качество жизни пациентов, ограничивают их работоспособность, что обусловливает определенный социальный и экономический ущерб от этих заболеваний. В связи с чем вопросы повышения качества противоопухолевого лечения являются одними из приоритетных вопросов в здравоохранении сегодня. Целью настоящего исследования является поиск новых возможных инструментов и подходов для повышения качества противоопухолевого лечения пациентов на разных уровнях, в том числе клиническом и образовательном. Существенно изменить и улучшить качество онкологической помощи пациентам возможно за счет инструментов и технологий сопроводительной терапии, в том числе и стоматологического сопровождения, клиническая значимость которого сегодня критически недооценивается. Совершенствование методов сопроводительной терапии — мультидисциплинарная проблема, которая может и должна быть решена исключительно в контексте междисциплинарного взаимодействия специалистов разного профиля. В настоящее время развитие стоматологического сопровождения ограничено рядом факторов, например клинических или организационных, но одним из наиболее значимых факторов, является недостаточное акцентирование внимания на данной проблеме в рамках медицинского образования. Безусловно, современные темпы развития медицины, внедрение новых технологий, в том числе и искусственного интеллекта, повышают требования к современному врачу-­специалисту и требуют от него обширных знаний, выходящих за рамки одной дисциплины, в том числе и наличие междисциплинарного мышления. Выводы. Таким образом, внедрение междисциплинарных подходов в обучении будущих врачей-стоматологов и врачей специальности «Лечебное дело», обучение студентов на стыке разных специальностей (онкология и стоматология, стоматология и гематология) способно повысить качество стоматологического сопровождения в частности и качество противоопухолевого лечения в целом.</p></trans-abstract><kwd-group xml:lang="en"><kwd>interdisciplinarity</kwd><kwd>supportive therapy</kwd><kwd>dental supporting care in cancer patients</kwd><kwd>medical education</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>междисциплинарность</kwd><kwd>сопроводительная терапия</kwd><kwd>стоматологическое сопровождение онкологических пациентов</kwd><kwd>медицинское образование</kwd></kwd-group><funding-group/></article-meta><fn-group/></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Kaprin AD, Starinsky VV, Shakhzadova AO. The state of oncological care for the population of Russia in 2023. Moscow: P.A. Herzen Moscow Oncology Research Institite — branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; 2024.239 p. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Каприн А.Д., Старинский В.В., Шахзадова А.О. Состояние онкологической помощи населению России в 2023 году. М.: МНИОИ им. П.А. Герцена — филиал ФГБУ «НМИЦ радиологии» Минздрава России, 2024. 239 с.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Shakhzadova AO, Starinsky VV, Lisichnikova IV. The state of cancer care for the population of Russia in 2022. Siberian journal of oncology. 2023;22(5):5–13. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Шахзадова А. О., Старинский В.В., Лисичникова И.В. Состояние онкологической помощи населению России в 2022 году // Сибирский онкологический журнал. 2023. Т. 22. № . 5. С. 5–13.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Alymov YuV, Ignatova A., Romanov IS. Clinical guidelines and expediency of using 5‑aminolevulinic acid for intraoperative visualization of margins of malignant tumors of the oral cavity. Head and Neck Tumors (HNT). 2022;12(2):33–40. (In Russian)</mixed-citation><mixed-citation xml:lang="ru">Алымов Ю. В., Игнатова А.В., Романов И.С. Клинические рекомендации и практическая целесообразность применения 5‑аминолевулиновой кислоты с целью интраоперационной визуализации границ злокачественных опухолей полости рта //Опухоли головы и шеи. 2022. Т. 12. № . 2. С. 33–40.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Gevorkov A R, Boyko AV, Bolotina LV, Shashkov SV, Abuzarova GR, Sarmanaeva RR. Results of implementation of a program of individual support of chemoradiation therapy in patients with head and neck tumors. Head and Neck Tumors (HNT). 2020;10(4): 60–73. doi:10.17650/2222-1468-2020-10-4-60-73</mixed-citation><mixed-citation xml:lang="ru">Геворков А.Р., Бойко А.В., Болотина Л.В., Шашков С.В., Абузарова Г.Р., Сарманаева Р.Р. Результаты внедрения индивидуальной программы терапии сопровождения пациентов с опухолями головы и шеи, проходящих химиолучевую терапию //Опухоли головы и шеи. 2020. Т. 10. № . 4. С. 60–73.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Elad S, Cheng KKF, Lalla RV, Yarom N, Hong C, Logan R M, Bowen J, Gibson R, Saunders DP, Zadik Y, Ariyawardana A, Correa ME, Ranna V, Bossi P. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2020;126(19):4423–4431. doi:10.1002/cncr.33100</mixed-citation><mixed-citation xml:lang="ru">Elad S., Cheng K.K. F., Lalla R.V., Yarom N., Hong C., Logan R.M., Bowen J., Gibson R., Saunders D.P., Zadik Y., Ariyawardana A., Correa M.E., Ranna V., Bossi P. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy //Cancer. 2020. Т. 126. № . 19. С. 4423–4431.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Andreev PY, Moshurov IP, Korotkih NV. Malignant neoplasms ozone therapy. RUDN Journal of Medicine. 2024;28(4):466–487. doi: 10.22363/2313-0245-2024-28-4-466-487 (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Андреев П.Ю., Мошуров И.П., Коротких Н.В., Шишкина В.В., Самойленко Т.В., Горюшкина Е.С., Антакова Л.Н. Озонотерапия злокачественных новообразований // Вестник Российского университета дружбы народов. Серия: Медицина. 2024. Т. 28. № 4. C. 466–487. doi: 10.22363/2313-0245-2024-28-4-466-487</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Aedinova IV, Volkova VL, Svetitsky PV, Bauzhadze MV, Islamova EF. Surgical treatment of cancer of the mucous membrane of the posterior parts of the oral cavity and oropharynx using mandibulotomy. Modern problems of science and education. 2016;3:23–27. (In Russian)</mixed-citation><mixed-citation xml:lang="ru">Аединова И.В., Волкова В.Л., Светицкий П.В., Баужадзе М.В., Исламова Е.Ф. Хирургическое лечение рака слизистой оболочки задних отделов полости рта и ротоглотки с применением мандибулотомии // Современные проблемы науки и образования. 2016. № . 3. С. 190–190.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Titova VA, Snigireva GP, Petrovsky YuV, Telysheva E N. Modern approaches to radiation treatment of oral tumors. Siberian journal of oncology. 2016;15(5):47–54. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Титова В.А., Снигирева Г.П., Петровский В.Ю., Телышева Е.Н. Современные подходы к лучевому лечению опухолей полости рта // Сибирский онкологический журнал. 2016. Т. 15. № 5. С. 47–54.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Artamonova EV, Bazin IS, Baranova OYu, Besova NS, Boychenko EI. Guide to chemotherapy of tumor diseases. Practical Medicine. 2018. 686 p. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Артамонова Е.В., Базин И.С., Баранова О.Ю., Бесова Н.С., Бойченко Е.И.. Руководство по химиотерапии опухолевых заболеваний. М.: Практическая медицина. 2018. 686 с.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Kopnin BP. Neoplastic cell: main properties and mechanisms of occurrence. Practical Oncology. 2002;4:229–235. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Копнин Б.П. Неопластическая клетка: основные свой­ства и механизмы их возникновения // Практическая онкология. 2002. Т. 3. № 4. С. 229–235.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Rivera F, García-­Castano A, Vega N, Vega-­Villegas ME, Gutierrez-­Sanz L. Cetuximab in metastatic or recurrent head and neck cancer: the EXTREME trial. Expert Rev. Anticancer Ther. 2009;9(10):1421–1428.</mixed-citation><mixed-citation xml:lang="ru">Rivera F., García-­Castaño A., Vega N., Vega-­Villegas M. E., Gutiérrez-­Sanz L. Cetuximab in metastatic or recurrent head and neck cancer: the extreme trial // Expert review of anticancer therapy. 2009. Т. 9. № 10. С. 1421–1428.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Vermorken JB, Mesia R, Rivera F, Remenar E, Kawecki A, Rottey S, Erfan J, Zabolotnyy D, Kienzer H R, Cupissol D, Peyrade F, Benasso M, Vynnychenko I, De Raucourt D, Bokemeyer C, Schueler A, Amellal N, Hitt R. Platinum-­based chemotherapy plus cetuximab in head and neck cancer. N. Engl. J. Med. 2008;359(11):116–1127.</mixed-citation><mixed-citation xml:lang="ru">Vermorken J. B., Mesia R., Rivera F., Remenar E., Kawecki A., Rottey S., Erfan J., Zabolotnyy D., Kienzer H.R., Cupissol D., Peyrade F., Benasso M., Vynnychenko I., De Raucourt D., Bokemeyer C., Schueler A., Amellal N., Hitt, R. Platinum-­based chemotherapy plus cetuximab in head and neck cancer // New England Journal of Medicine. 2008. Т. 359. № 11. С. 1116–1127.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Safarov DA, Mudunov AM, Dolgushin BI, Akhundov AA, Zaderenko IA, Peshko DA. Results of conservative treatment of locally advanced larynx squamous cell carcinoma using intraarterial regional polychemotherapy. Head and Neck Tumors (HNT). 2021;11(1):41–50. (In Russian.)</mixed-citation><mixed-citation xml:lang="ru">Сафаров Д.А., Мудунов А.М., Долгушин Б.И., Ахундов А.А., Задеренко И.А., Пешко Д.А. Результаты консервативного лечения местно-­распространенного плоскоклеточного рака гортани с применением внутриартериальной регионарной полихимиотерапии //Опухоли головы и шеи. 2021. Т. 11. № 1. С. 41–50.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Kamsvåg T, Svanberg A, Legert KG, Arvidson J, von Essen L, Mellgren K, Toporski J, Winiarski J, Ljungman G. Prevention of oral mucositis with cryotherapy in children undergoing hematopoietic stem cell transplantations-a feasibility study and randomized controlled trial. Support. Care Cancer. 2020;28:1–11.</mixed-citation><mixed-citation xml:lang="ru">Kamsvag, T., Svanberg, A., Legert, K.G., Arvidson, J., von Essen, L., Mellgren, K., Toporski, J., Winiarski, J., Ljungman, G. Prevention of oral mucositis with cryotherapy in children undergoing hematopoietic stem cell transplantations — a feasibility study and randomized controlled trial // Supportive Care in Cancer. 2020. Т. 28. С. 4869–4879.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Scully C, Epstein J, Sonis S. Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy: part 1, pathogenesis and prophylaxis of mucositis. Head Neck. 2003;25(12):1057–1070. doi:10.1002/hed.10318</mixed-citation><mixed-citation xml:lang="ru">Scully C., Epstein J., Sonis S. Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy: part 1, pathogenesis and prophylaxis of mucositis // Head &amp; Neck: Journal for the Sciences and Specialties of the Head and Neck. 2003. Т. 25. № 12. С. 1057–1070.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">Epstein JB, Schubert MM. Managing pain in mucositis. Semin Oncol Nurs. 2004;20(1):30–37. doi: 10.1053/j.soncn.2003.10.006</mixed-citation><mixed-citation xml:lang="ru">Epstein J.B., Schubert M.M. Managing pain in mucositis // Seminars in oncology nursing. 2004. Т. 20. № 1. С. 30–37.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">Argiris A, Brockstein B E, Haraf DJ, Stenson KM, Mittal BB, Kies MS, Rosen F R, Jovanovic B, Vokes EE. Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy. Clin Cancer Res. 2004;10:1956–1962.</mixed-citation><mixed-citation xml:lang="ru">Argiris A., Brockstein B.E., Haraf D.J., Stenson K.M., Mittal B.B., Kies M.S., Rosen F.R., Jovanovic B., Vokes E.E. Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy // Clinical cancer research. 2004. Т. 10. № 6. С. 1956–1962.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">Lapteva ES, Aryev AL, Tsutsunava MR. Comorbidity/multimorbidity problem of terminology and application of index indicators. Advances in gerontology. 2021;34(3):336–344. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Лаптева Е.С., Арьев А.Л., Цуцунава М.Р., Арьева Г.Т., Дьячкова-­Герцева Д.С. Коморбидность/полиморбидность проблемы терминологии и применения индексовых показателей (обзор) // Успехи геронтологии. 2021. Т. 34. № 3. С. 336–344.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">Jumaniyazova ED, Sentyabreva AV, Kosyreva A.M, Lokhonina AV. Molecular genetic signatures of head and neck squamous cell carcinoma and their changes induced by proton irradiation. RUDN Journal of Medicine. 2024;28(4):413–426. doi: 10.22363/2313-0245-2024-28-4-413-426 (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Джуманиязова Э.Д., Сентябрева А.В., Косырева А.М., Лохонина А.В. Молекулярно-­генетические сигнатуры плоскоклеточного рака головы и шеи и их изменения, индуцированные протонным облучением // Вестник Российского университета дружбы народов. Серия: Медицина. 2024. Т. 28. № 4. C. 413–426.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">Mudunov AM, Pak MB, Wolf LYa. The role of nutritional support in treatment of head and neck tumors: clinical case. Head and Neck Tumors (HNT). 2022;12(3):86–94. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Мудунов А.М., Пак М.Б., Вольф Л.Я. Роль нутритивной поддержки в лечении опухолей головы и шеи: клинический случай //Опухоли головы и шеи. 2022. Т. 12. № 3. С. 86–94.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">Dzhereley AA, Romanenko IG, Arakelyan КA, Kryuchkov DY, Gorobets SМ, Bobkova SA. Correlation features of oral mucosits and psychological status in patients with squamous cell carcinoma of the oral mucosa at the stage of chemoradiation therapy. Bulletin of the Medical Institute «REAVIZ». 2021;(2):100–105. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Джерелей А.А., Романенко И.Г., Аракелян К.А., Крючков Д.Ю., Горобец С.М, Бобкова С.А. Корреляционные особенности мукозита полости рта и психологического статуса у пациентов с плоскоклеточным раком слизистой оболочки рта, находящихся на этапе химиолучевой терапии // Вестник медицинского института «Реавиз»: реабилитация, врач и здоровье. 2021. № 2 Т. 50. С. 100–105.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">Reyes-­Gibby CC, Wang J, Zhang L, Peterson CB, Do KA, Jenq RR, Shelburne S, Shah DP, Chambers MS, Hanna EY, Yeung SJ, Shete S. Oral Microbiome and Onset of Oral Mucositis in Patients with Squamous Cell Carcinoma of the Head and Neck. Cancer. 2020;126(23):5124–36. doi: 10.1002/cncr.33161</mixed-citation><mixed-citation xml:lang="ru">Reyes-­Gibby C.C., Wang J., Zhang L., Peterson C.B., Do K.A., Jenq R.R., Shelburne S., Shah D.P., Chambers M.S., Hanna E.Y., Yeung S.J., Shete S. Oral microbiome and onset of oral mucositis in patients with squamous cell carcinoma of the head and neck // Cancer. 2020. Т. 126. № 23. С. 5124–5136.</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">Bagirova NS, Petukhova IN, Grigorievskaya ZV, Sytov A, Slukin PV, Goremykina EA, Khokhlova OE, Fursova NK, Kazimov AE. Oral microbiota in patients with oropharyngeal cancer with an emphasis on Candida spp. Head and Neck Tumors (HNT). 2022;12(3):71–85. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Багирова Н.С., Петухова И.Н., Григорьевская З.В., Сытов А.В., Слукин П.В., Горемыкина Е.А., Хохлова О.Е., Фурсова Н.К., Казимов А.Э. Микробиота полости рта у больных раком орофарингеальной области с акцентом на Candida spp // Опухоли головы и шеи. 2022. Т. 12. № 3. С. 71–85.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">Hong BY, Sobue T, Choquette L, Dupuy AK, Thompson A, Burleson JA, Salner AL, Schauer PK, Joshi P, Fox E, Shin DG, Weinstock GM, Strausbaugh LD, Dongari-­Bagtzoglou A, Peterson DE, Diaz PI. Chemotherapy-­induced oral mucositis is associated with detrimental bacterial dysbiosis. Microbiome. 2019;7(1):66. doi: 10.1186/s40168-019-0679-5</mixed-citation><mixed-citation xml:lang="ru">Hong B.Y., Sobue T., Choquette L., Dupuy A.K, Thompson A., Burleson J.A., Andrew L., Schauer S.P.K., Joshi P., Fox E., Shin D.G., Weinstock G.M., Strausbaugh L.D., Dongari-­Bagtzoglou A., Peterson D.E, Diaz P.I. Chemotherapy-­induced oral mucositis is associated with detrimental bacterial dysbiosis // Microbiome. 2019. Т. 7. С. 1–18.</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">Shikhlyarova AI, Zhukova GV. Pathophysiological aspects of the use of accompanying therapy in oncology. Crimean Journal of Experimental and Clinical Medicine. 2020;10 (3):124. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Шихлярова А.И., Жукова Г.В. Патофизиологические аспекты применения сопроводительной терапии в онкологии // Крымский журнал экспериментальной и клинической медицины. 2020. Т. 10. № 3. С. 124–124.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">Ballyuzek MF, Ionova AK, Mashkova MV, Stepanov BP, Chagunava OL. Organization of rehabilitation programs for cancer patients based on an interdisciplinary approach. Research and Practical Medicine Journal. 2018;5(4):91–97. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Шмеркевич А. Б., Водолагин А.В., Балакина Д.Д. Междисциплинарные аспекты реабилитации онкологических больных в нетерминальной ситуации болезни // Саратовский научно-­медицинский журнал. 2017. Т. 13. № 4. С. 806–808.</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">Velcheva AI, Zenkevich AA, Boshataev DT. Oral mucositis as a complication of polychemotherapy. Academic Journal of Western Siberia. 2022;18(2):25–28 (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Вельчева А. И., Зенкевич А.А., Бошатаев Д.Т. Оральные мукозиты как осложнение полихимиотерапии // Академический журнал Западной Сибири. 2022. Т. 18. № 2(95). С. 25–28.</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">Golubev PV, Bolotina LV, Gevorkov AR, Deshkina TI, Boyko AV, Kaprin AD. The effectiveness of a dual-component regimen of induction chemotherapy in the treatment of HPV-positive oropharyngeal squamous cell carcinoma. Siberian journal of oncology. 2023;22(2):26–33. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Голубев П.В., Болотина Л.В., Геворков А.Р., Дешкина Т.И., Бойко А.В., Каприн А.Д. Эффективность двухкомпонентного режима индукционной химиотерапии при лечении ВПЧ-позитивного плоскоклеточного рака ротоглотки // Сибирский онкологический журнал. 2023. Т. 22. № 2. С. 26–33.</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">Blakaj A, Bonomi M, Gamez ME, Blakaj DM. Oral mucositis in head and neck cancer: Evidence-­based management and review of clinical trial data. Oral Oncol. 2019;95:29–34. doi: 10.1016/j.oraloncology.2019.05.013</mixed-citation><mixed-citation xml:lang="ru">Blakaj A., Bonomi M., Gamez M.E., Blakaj D.M. Oral mucositis in head and neck cancer: Evidence-­based management and review of clinical trial data // Oral oncology. 2019. Т. 95. С. 29–34.</mixed-citation></citation-alternatives></ref><ref id="B30"><label>30.</label><citation-alternatives><mixed-citation xml:lang="en">Kusiak A, Jereczek-­Fossa BA, Cichońska D, Alterio D. Oncological-­Therapy Related Oral Mucositis as an Interdisciplinary Problem-­Literature Review. Int J Environ Res Public Health. 2020;17(7):2464. doi: 10.3390/ijerph17072464</mixed-citation><mixed-citation xml:lang="ru">Kusiak A., Jereczek-­Fossa B. A., Cichonska D., Alterio D. Oncological-­therapy related oral mucositis as an interdisciplinary problem — literature review // International journal of environmental research and public health. 2020. Т. 17. №  7. С. 2464.</mixed-citation></citation-alternatives></ref><ref id="B31"><label>31.</label><citation-alternatives><mixed-citation xml:lang="en">Kudasova EO, Kochurova EV, Nikolenko VN, Panferova OI. Dental treatment of patients with squamous cell carcinoma of the oral mucosa. Russian Dental Journal. 2021;25(3):259–268. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Кудасова Е.О., Кочурова Е.В., Николенко В.Н., Панферова О.И. Стоматологическое лечение пациентов при плоскоклеточном раке слизистой оболочки полости рта // Российский стоматологический журнал. 2021. Т. 25. № 3. C. 259–266.</mixed-citation></citation-alternatives></ref><ref id="B32"><label>32.</label><citation-alternatives><mixed-citation xml:lang="en">Kasoev VG, Gabaraev DE. Mucositis as a complication of antitumor therapy. Prevention and principles of treatment. Scientific Leader. 2023;4(102):41–43. (In Russian). https://scilead.ru/article/3938‑mukozit-kak-oslozhnenie-­protivoopukholevoj-te</mixed-citation><mixed-citation xml:lang="ru">Касоев В.Г., Габараев Д.Э. Мукозит, как осложнение противоопухолевой терапии. Профилактика и принципы лечения // 2023. № 4 (102). https://scilead.ru/article/3938‑mukozit-kak-oslozhnenie-­protivoopukholevoj-te</mixed-citation></citation-alternatives></ref><ref id="B33"><label>33.</label><citation-alternatives><mixed-citation xml:lang="en">Dharman S, Shanmugasundaram K, Sampath RK. A Systematic Review and Meta-­Analysis on the Efficacy of Curcumin/Turmeric for the Prevention and Amelioration of Radiotherapy/Radiochemotherapy Induced Oral Mucositis in Head and Neck Cancer Patients. Asian Pac J Cancer Prev. 2021;22(6):1671–1684. doi:10.31557/APJCP.2021.22.6.1671</mixed-citation><mixed-citation xml:lang="ru">Dharman S.G.M., Shanmugasundaram K., Sampath R.K. A Systematic Review and Meta-­Analysis on the Efficacy of Curcumin/Turmeric for the Prevention and Amelioration of Radiotherapy/Radiochemotherapy Induced Oral Mucositis in Head and Neck Cancer Patients // Asian Pacific journal of cancer prevention: APJCP. 2021. Т. 22. № 6. Р. 1671–1684.</mixed-citation></citation-alternatives></ref><ref id="B34"><label>34.</label><citation-alternatives><mixed-citation xml:lang="en">Alcantara MJ, Pandy JG, Sebastian MR. 338P — Vitamin E in the treatment of chemotherapy and radiation-­induced mucositis: A meta-analysis of randomized controlled trials. Ann Oncol. 2020;31(6):1371–1377. https://doi.org/10.1016/j.annonc.2020.10.332</mixed-citation><mixed-citation xml:lang="ru">Alcantara M.J.E., Pandy J.G.P., Sebastian M R.C. Vitamin E in the treatment of chemotherapy and radiation-­induced mucositis: A meta-analysis of randomized controlled trials // Annals of Oncology. 2020. Т. 31. Р. 1372–1373. https://doi.org/10.1016/j.annonc.2020.10.332</mixed-citation></citation-alternatives></ref><ref id="B35"><label>35.</label><citation-alternatives><mixed-citation xml:lang="en">Brown TJ, Gupta A. Management of cancer therapy-­associated oral mucositis. JCO Oncol Pract. 2020;16:103–9. doi: 10.1200/JOP.19.00652</mixed-citation><mixed-citation xml:lang="ru">Brown TJ, Gupta A. Management of Cancer Therapy-­Associated Oral Mucositis // JCO Oncol Pract. 2020. Т. 16. № 3. С. 103–109.</mixed-citation></citation-alternatives></ref><ref id="B36"><label>36.</label><citation-alternatives><mixed-citation xml:lang="en">Sultanov RR. Interdisciplinary interaction of doctors as one of the ways to increase the effectiveness of the treatment process. Humanities and Social Sciences. 2013;2:231–243. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Султанов Р.Р. Междисциплинарное взаимодействие врачей как один из способов повышения эффективности процесса лечения //Гуманитарные и социальные науки. 2013. № 2. С. 231–243.</mixed-citation></citation-alternatives></ref><ref id="B37"><label>37.</label><citation-alternatives><mixed-citation xml:lang="en">Roitberg GE, Tyulkina EE, Dorosh ZhV, Filatov RE, Anikeeva OYu. Organization of multidisciplinary rehabilitation of oncology patients. Bulletin of Restorative Medicine. 2019;5(93):14–20. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Ройтберг Г.Е., Тюлькина Е.Е., Дорош Ж.В., Филатов Р.Е., Аникеева О.Ю. Организация мультидисциплинарной реабилитации пациентов онкологического профиля // Вестник восстановительной медицины. 2019. Т. 93. № 5. С. 14–20.</mixed-citation></citation-alternatives></ref><ref id="B38"><label>38.</label><citation-alternatives><mixed-citation xml:lang="en">Kostin AA, Samsonov YV. Management structure and organization of oncological careю. RUDN Journal of Medicine. 2024;28.(2):206–215. doi: 10.22363/2313-0245-2024-28-2-206-215</mixed-citation><mixed-citation xml:lang="ru">Костин А.А., Самсонов Ю.В. Структура управления и организации онкологической помощи // Вестник Российского университета дружбы народов. Серия: Медицина. 2024. Т. 28. № 2. C. 206–215. doi: 10.22363/2313-0245-2024-28-2-206-215</mixed-citation></citation-alternatives></ref><ref id="B39"><label>39.</label><citation-alternatives><mixed-citation xml:lang="en">Lopanova EV, Lalov Yu V. Integration of medical and pedagogical technologies in the professional training of a future doctor. Problems of modern science and education. 2017;14(96):72–78. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Лопанова Е. В., Лалов Ю.В. Интеграция медицинских и педагогических технологий в профессиональной подготовке будущего врача // Проблемы современной науки и образования. 2017. Т. 96. № 14. С. 72–78.</mixed-citation></citation-alternatives></ref><ref id="B40"><label>40.</label><citation-alternatives><mixed-citation xml:lang="en">Bergen TA, Pukhalsky AN. Multidisciplinarity and interdisciplinarity as opportunities for the development of the system of medical care in the Russian Federation. Bulletin of Roszdravnadzor. 2023; 1:28–34. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Берген Т.А., Пухальский А.Н. Мультидисциплинарность и междисциплинарность как возможности для развития системы оказания медицинской помощи в Российской Федерации // Вестник Росздравнадзора. 2023. Т. 1. С. 28–34</mixed-citation></citation-alternatives></ref><ref id="B41"><label>41.</label><citation-alternatives><mixed-citation xml:lang="en">Aksenova EI. Organization of the work of interdisciplinary teams in primary healthcare. Moscow Medicine. 2023;1(53):34–41. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Аксенова Е.И. Организация работы междисциплинарных команд в первичном звене здравоохранения // Московская медицина. 2023. Т. 53. № 1. С. 34–41.</mixed-citation></citation-alternatives></ref><ref id="B42"><label>42.</label><citation-alternatives><mixed-citation xml:lang="en">Martykenova DS, Aimbetova GE, Bagiyarova FA. Foreign experience in the functioning of multidisciplinary teams of psycho-­social profile in outpatient clinics. Bulletin of KazNMU. 2019;2: 378–381. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Мартыкенова Д.С., Аимбетова Г.Е., Багиярова Ф.А. Зарубежный опыт функционирования мультидисциплинарных команд психо-­социального профиля в амбулаторно-­поликлинических организациях // Вестник КазНМУ. 2019. № 2.</mixed-citation></citation-alternatives></ref><ref id="B43"><label>43.</label><citation-alternatives><mixed-citation xml:lang="en">Pavlovsky VV. Distinctive features of our advanced training programs are focus on practice and interdisciplinarity. Doctor.Ru. 2022;2. (In Russian).</mixed-citation><mixed-citation xml:lang="ru">Павловский В.В. Отличительные особенности наших программ повышения квалификации — ориентация на практику и междисциплинарность // Доктор.Ру. 2022. № 2.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
