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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">38301</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2024-28-1-104-113</article-id><article-id pub-id-type="edn">UNHBRQ</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PHYSIOLOGY. EXPERIMENTAL PHYSIOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ФИЗИОЛОГИЯ. ЭКСПЕРИМЕНТАЛЬНАЯ ФИЗИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Combination of neuromuscular block monitoring and hand grip strength assessment for patients undergoing emergency abdominal surgery</article-title><trans-title-group xml:lang="ru"><trans-title>Комбинация мониторинга нервно-мышечного блока и оценки силы захвата рук у пациентов, перенесших экстренную абдоминальную операцию</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-7058-5021</contrib-id><name-alternatives><name xml:lang="en"><surname>Dhunputh</surname><given-names>Neelam</given-names></name><name xml:lang="ru"><surname>Данпут</surname><given-names>Н.</given-names></name></name-alternatives><email>dhunputhneelam@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4272-0957</contrib-id><name-alternatives><name xml:lang="en"><surname>Petrova</surname><given-names>Marina V.</given-names></name><name xml:lang="ru"><surname>Петрова</surname><given-names>М. В.</given-names></name></name-alternatives><email>dhunputhneelam@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3467-7170</contrib-id><name-alternatives><name xml:lang="en"><surname>Moroz</surname><given-names>Victor V.</given-names></name><name xml:lang="ru"><surname>Мороз</surname><given-names>В. В.</given-names></name></name-alternatives><email>dhunputhneelam@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4462-1530</contrib-id><name-alternatives><name xml:lang="en"><surname>Butrov</surname><given-names>Andrey V.</given-names></name><name xml:lang="ru"><surname>Бутров</surname><given-names>А. В.</given-names></name></name-alternatives><email>dhunputhneelam@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1972-7336</contrib-id><name-alternatives><name xml:lang="en"><surname>Magomedov</surname><given-names>Marat F.</given-names></name><name xml:lang="ru"><surname>Магомедов</surname><given-names>М. Ф.</given-names></name></name-alternatives><email>dhunputhneelam@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">RUDN University</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2024</year></pub-date><volume>28</volume><issue>1</issue><issue-title xml:lang="en">DENTISTRY</issue-title><issue-title xml:lang="ru">СТОМАТОЛОГИЯ</issue-title><fpage>104</fpage><lpage>113</lpage><history><date date-type="received" iso-8601-date="2024-03-18"><day>18</day><month>03</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Dhunputh N., Petrova M.V., Moroz V.V., Butrov A.V., Magomedov M.F.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Данпут Н., Петрова М.В., Мороз В.В., Бутров А.В., Магомедов М.Ф.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Dhunputh N., Petrova M.V., Moroz V.V., Butrov A.V., Magomedov M.F.</copyright-holder><copyright-holder xml:lang="ru">Данпут Н., Петрова М.В., Мороз В.В., Бутров А.В., Магомедов М.Ф.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/38301">https://journals.rudn.ru/medicine/article/view/38301</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Relevance. The hand grip strength measurement together with neuromuscular block monitoring played an important role during surgery. They both helped in losing less time during surgery and also facilitate the task of the surgeon. The aim of this study was to reduce time on intubation, facilitate the task of the surgeon and to limit post-surgical pain. In rehabilitation, hand grip strength helps in determining further recuperation measures after a surgery. There are three fundamental principles for an anesthesiologist to ensure that the patient after combined endotracheal anesthesia can be extubated, the first one is to ask the patient to move his head forward, the second one is to ask the patient whether the intubation tube is disturbing him in his mouth and the third most important one is to make the patient hold his wrist very firmly. Materials and Methods. Monitoring of muscle relaxant on induction, intra and post-surgery is carried out using a TOF Watch SX in coordination with handgrip strength measurement on 46 patients aged from 18 to 60 years of BMI of 18-30 kg/m² 15min before endotracheal intubation and 15min, 45min and 210min post extubation by using a dynamometer “MEGEON 34090” to help us understand whether after extubation muscle strength changes and to what extent. Also, pre-anesthesiology protocol, combined endotracheal protocol, Microsoft excel advanced, monitoring of hemodynamics, ECG, PEEP, PCO2, PO2, respiratory volume using Drager Fabius. Results and Discussion. The results showed that to reach deep muscle relaxation both atracurium benzilate (FKP Kursk Biofabric company, Kursk, Russia) at TOF 0 took 258.5 ±  83.5 secs and Cisatracurium benzilate (ZAO Obninsk Chemical pharmaceutical company, Obninsk, Russia) at TOF0-252.4 ± 100.1 secs in emergency patients and basically hand grip strength also was lesser as compared to planned cholecystectomy patients. Conclusion. Rehabilitation was necessary for patients undergoing massive abdominal emergency surgeries underlying the fact that on a pain scale 10/10 post surgery, further treatments should be implemented to reduce pain, reduce residual neuromuscular block and muscle weakness after extubation at TOF 90-95%.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Актуальность. Измерение силы захвата руки вместе с мониторингом нервно-­мышечного блока сыграли важную роль во время операции. Они оба помогли сократить время, потраченное на операцию, а также облегчили задачу хирурга. Целью этого исследования было сократить время интубации, облегчить задачу хирурга и ограничить послеоперационную боль. В реабилитации сила захвата руки помогает определить дальнейшие меры восстановления после операции. Есть три основополагающих принципа для анестезиолога обеспечивающих возможность экстубации пациента после комбинированной эндотрахеальной анестезии: первый - попросить пациента подвинуть голову вперед, второй - спросить пациента, не беспокоит ли его интубационная трубка во рту, и третий по важности шаг - заставить пациента очень крепко держать запястье. Материалы и методы. Мониторинг миорелаксанта при индукции, во время и после операции проводился с помощью TOF Watch SX в сочетании с измерением силы захвата у 46 пациентов в возрасте от 18 до 60 лет с ИМТ 18-30 кг/м² за 15 минут до эндотрахеальной интубации и через 15, 45 и 210 минут после экстубации с использованием динамометра «МЕГЕОН 34090», чтобы помочь нам понять, меняется ли после экстубации мышечная сила и в какой степени. Также, преданестезиологический протокол, комбинированный эндотрахеальный протокол, мониторинг гемодинамики, ЭКГ, ПДКВ, PCO2, PO2, дыхательного объема с помощью Drager Fabius. Результаты и обсуждение. Результаты показали, что для достижения глубокой мышечной релаксации как атракурию (ФКП «Курская Биофабрика», Курск, Россия) при TOF 0 требовалось 258,5 ± 83,5 с, так и цисатракурию (ЗАО «Обнинская химико-­фармацевтическая компания», Обнинск, Россия) при TOF0-252,4 ± 100,1 с у экстренных пациентов, а в основном сила захвата рук также была меньше по сравнению с пациентами с плановой холецистэктомией. Выводы. Реабилитация была необходима пациентам, перенесшим обширные экстренные операции на брюшной полости, поскольку при шкале боли 10/10 после операции необходимо проводить дальнейшее лечение для уменьшения боли, уменьшения остаточного нервно-­мышечного блока и мышечной слабости после экстубации при TOF 90-95%.</p></trans-abstract><kwd-group xml:lang="en"><kwd>hand grip strength</kwd><kwd>neuromuscular block</kwd><kwd>atracurium benzilate</kwd><kwd>cisatracurium benzilate</kwd><kwd>rehabilitation</kwd><kwd>emergency abdominal surgery</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>сила хвата руки</kwd><kwd>нервно-мышечный блок</kwd><kwd>атракурия бензилат</kwd><kwd>цисатракурия бензилат</kwd><kwd>реабилитация</kwd><kwd>экстренная абдоминальная хирургия</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The Research work was funded by RUDN University.</funding-statement><funding-statement xml:lang="ru">Исследование выполнено при поддержке Программы стратегического академического лидерства РУДН.</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Chandrasekaran B, Ghosh A, Prasad C, Krishnan K, Chandrasharma B. 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