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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">38297</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2024-28-1-57-67</article-id><article-id pub-id-type="edn">UCWVAI</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Stomatology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Дантистика</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Techniques for conservative treatment of peri-implantitis</article-title><trans-title-group xml:lang="ru"><trans-title>Методы консервативного лечения периимплантита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5321-3304</contrib-id><contrib-id contrib-id-type="spin">1109-6468</contrib-id><name-alternatives><name xml:lang="en"><surname>Burlakova</surname><given-names>Lyubov A.</given-names></name><name xml:lang="ru"><surname>Бурлакова</surname><given-names>Л. А.</given-names></name></name-alternatives><email>shererrrr9@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8980-6235</contrib-id><contrib-id contrib-id-type="spin">7254-4306</contrib-id><name-alternatives><name xml:lang="en"><surname>Dymnikov</surname><given-names>Alexander B.</given-names></name><name xml:lang="ru"><surname>Дымников</surname><given-names>А. Б.</given-names></name></name-alternatives><email>shererrrr9@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">RUDN University</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2024</year></pub-date><volume>28</volume><issue>1</issue><issue-title xml:lang="en">DENTISTRY</issue-title><issue-title xml:lang="ru">СТОМАТОЛОГИЯ</issue-title><fpage>57</fpage><lpage>67</lpage><history><date date-type="received" iso-8601-date="2024-03-18"><day>18</day><month>03</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Burlakova L.A., Dymnikov A.B.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Бурлакова Л.А., Дымников А.Б.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Burlakova L.A., Dymnikov A.B.</copyright-holder><copyright-holder xml:lang="ru">Бурлакова Л.А., Дымников А.Б.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/38297">https://journals.rudn.ru/medicine/article/view/38297</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Relevance. Dental implants are widely used to restore the patient’s teeth. They have become a worthy alternative to removable dentures. With the accumulation of clinical experience, the indications for dental implantation expanded, and as a result, the evaluation of long-term results became possible. In parallel with the expansion of clinical use of dental implants and the introduction of the technology into everyday practice, the experience of complications and errors accumulated, and from single publications in the 1990s, at the very beginning of development, to large-­scale studies in the 10s. And if in the early period of implantology development the success of treatment was mainly associated with implant survival, then modern research focuses on the state of tissues around the implant, and the influence of processes in them on the overall outcome of treatment. One of the main complications is inflammation of peri-implant tissues - peri-implantitis. Modern authors define peri-implantitis as an inflammatory process affecting the tissues around a functionally integrated implant, resulting in loss of supporting bone. Continued bone loss around the implant can significantly impair implant stability and function. The authors review the scientific literature describing experimental conservative treatment protocols for peri-implantitis and attempts to achieve osseointegration. Conclusion. The reviewed literature advocated various methods of surgical regenerative treatment for peri-implantitis, including the use of bone substitutes, methods of detoxification of implant surfaces, and the administration of antimicrobial agents. There are many different protocols for the treatment of peri-implantitis; they all share the same goal of reducing disease progression and bone loss by eliminating bacterial infection. The controversy over the proper approach to treating peri-implantitis and restoring osseointegration clearly demonstrates the need for more research to answer this question.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Актуальность. Дентальные имплантаты получили широкое применение для восстановления зубных рядов у пациента. Они стали достойной альтернативой съемным протезам. По мере накопления клинического опыта, ширились показания к дентальной имплантации, в результате чего стала возможной оценка отдаленных результатов. Параллельно с расширением клинического применения дентальных имплантатов и внедрением технологии в повседневную практику, накапливался и опыт осложнений и ошибок, и от единичных публикаций в 1990-х гг., в самом начале развития, до масштабных исследований в 10-х. И если в раннем периоде развития имплантологии успех лечения связывали в основном с выживаемостью имплантатов, то современные исследования фокусируются на состоянии тканей вокруг имплантата, и влиянию процессов в них на общий исход лечения. Одно из основных осложнений - воспаление периимплантных тканей - периимплантит. Современные авторы определяют периимплантит как воспалительный процесс, поражающий ткани вокруг функционально интегрированного имплантата, что приводит к потере опорной кости. Продолжающаяся потеря костной ткани вокруг имплантата может значительно ухудшить стабильность и функцию имплантата. Рассмотрена научная литература, в которой описываются протоколы эксперементального консерватичного лечения периимплантита и попытки добиться повторной остеоинтеграции. Выводы. В рассмотренной научной литературе пропагандировались различные методы хирургического регенеративного лечения периимплантита, включая использование заменителей кости, методы детоксикации поверхностей имплантатов, назначения противомикробных препаратов. Существует множество различных протоколов лечения периимплантита; все они объединены одной целью - снижение прогрессирования заболевания и потери костной ткани путем устранения бактериальной инфекции. Споры относительно правильного подхода к лечению периимплантита и восстановлению остеоинтеграции, очевидно, демонстрируют потребность в более расширенных исследованиях для ответа на этот вопрос.</p></trans-abstract><kwd-group xml:lang="en"><kwd>peri-implantitis</kwd><kwd>conservative treatment of peri-implantitis</kwd><kwd>osseointegration</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>периимплантит</kwd><kwd>консерватичное лечение периимплантита</kwd><kwd>остеоинтеграция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Pjetursson BE, Thoma D, Jung R, Zwahlen M, Zembic AA. Systematic review of the survival and complication rates of implant-­supported fixed dental prostheses (FDPs) after a mean observation period of at least 5 years. Clin Oral Implants Res. 2012;23:22. doi:10.1111/j.1600-0501.2012.02546.x</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Lang NP, Pjetursson BE, Tan K. 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