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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">38293</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2024-28-1-9-22</article-id><article-id pub-id-type="edn">TMYOTY</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Stomatology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Дантистика</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Magnetic field application in bone tissue regeneration: issue current status and prospects for method development</article-title><trans-title-group xml:lang="ru"><trans-title>Применение магнитного поля в регенерации костной ткани: современное состояние вопроса и перспективы развития метода</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3982-5512</contrib-id><name-alternatives><name xml:lang="en"><surname>Muraev</surname><given-names>Alexandr A.</given-names></name><name xml:lang="ru"><surname>Мураев</surname><given-names>А. А.</given-names></name></name-alternatives><email>ms.s.karina@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-8636-994X</contrib-id><name-alternatives><name xml:lang="en"><surname>Manukyan</surname><given-names>George G.</given-names></name><name xml:lang="ru"><surname>Манукян</surname><given-names>Г. Г.</given-names></name></name-alternatives><email>ms.s.karina@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4415-766X</contrib-id><name-alternatives><name xml:lang="en"><surname>Salekh</surname><given-names>Karina M.</given-names></name><name xml:lang="ru"><surname>Салех</surname><given-names>К. М.</given-names></name></name-alternatives><email>ms.s.karina@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5894-9524</contrib-id><name-alternatives><name xml:lang="en"><surname>Bonartsev</surname><given-names>Anton P.</given-names></name><name xml:lang="ru"><surname>Бонарцев</surname><given-names>А. П.</given-names></name></name-alternatives><email>ms.s.karina@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5611-3990</contrib-id><name-alternatives><name xml:lang="en"><surname>Volkov</surname><given-names>Alexey V.</given-names></name><name xml:lang="ru"><surname>Волков</surname><given-names>А. В.</given-names></name></name-alternatives><email>ms.s.karina@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">RUDN University</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Lomonosov Moscow State University</institution></aff><aff><institution xml:lang="ru">Московский государственный университет имени М.В. Ломоносова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2024</year></pub-date><volume>28</volume><issue>1</issue><issue-title xml:lang="en">DENTISTRY</issue-title><issue-title xml:lang="ru">СТОМАТОЛОГИЯ</issue-title><fpage>9</fpage><lpage>22</lpage><history><date date-type="received" iso-8601-date="2024-03-18"><day>18</day><month>03</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Muraev A.A., Manukyan G.G., Salekh K.M., Bonartsev A.P., Volkov A.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Мураев А.А., Манукян Г.Г., Салех К.М., Бонарцев А.П., Волков А.В.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Muraev A.A., Manukyan G.G., Salekh K.M., Bonartsev A.P., Volkov A.V.</copyright-holder><copyright-holder xml:lang="ru">Мураев А.А., Манукян Г.Г., Салех К.М., Бонарцев А.П., Волков А.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/38293">https://journals.rudn.ru/medicine/article/view/38293</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Relevance. Magnets have long been used to treat various diseases, especially in inflammatory processes. According to existing historical data, magnetotherapy was already used in ancient times by the Chinese, Egyptians and Greeks. Different magnetic field strengths affect cells in different ways, with medium-strength magnetic fields being the most widely used. The review presents a brief history and current state of the issue of using a magnetic field in bone tissue regeneration. Modern knowledge about the mechanisms of physiological and reparative regeneration, restoration of bone tissue is clarified, and modern areas of bone tissue engineering are considered, taking into account the characteristics of microcirculation and the effect of a magnetic field on the physiology of bone tissue and reparative regeneration. One of the key findings of the review is that the magnetic field improves bone tissue repair by influencing the metabolic behavior of cells. Studies show that magnetotherapy promotes the activation of cellular processes, accelerates the formation of new bone tissue and improves its quality. It is also noted that the magnetic field has a positive effect on microcirculation, improving the blood supply to tissues and facilitating a better supply of nutrients to the site of injury. This contributes to faster wound healing and early rehabilitation of patients. Conclusion. Magnetotherapy is one of the effective physical and rehabilitation methods of treatment that will become increasingly important in modern medicine. However, further research is needed to better understand the mechanisms of action of a magnetic field on bone tissue and to determine the optimal parameters for its application.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Актуальность . Магниты с давних времен использовались для лечения различных заболеваний, особенно при воспалительных процессах. Согласно существующим историческим данным, магнитотерапию применяли уже в древности китайцы, египтяне и греки. Разная сила магнитного поля по-разному влияет на клетки, при этом наиболее широко используются магнитные поля средней силы. В настоящем обзоре литературы представлены краткая история и современное состояние вопроса применения магнитного поля в регенерации костной ткани. Уточнены современные знания о механизмах физиологической и репаративной регенерации, восстановления костной ткани, а также рассмотрены современные направления инженерии костной ткани с учетом особенностей микроциркуляции и влияние магнитного поля на физиологию костной ткани и репаративную регенерацию. Одним из ключевых выводов обзора является то, что магнитное поле улучшает восстановление костной ткани, влияя на метаболическое поведение клеток. Исследования показывают, что магнитотерапия способствует активации клеточных процессов, ускоряет образование новой костной ткани и повышает ее качество. Также отмечается, что магнитное поле оказывает положительное влияние на микроциркуляцию, улучшая кровоснабжение тканей и способствуя лучшему поступлению питательных веществ к месту повреждения. Это способствует более быстрому заживлению ран и ранней реабилитации пациентов. Выводы. Магнитотерапия является одним из эффективных физических и реабилитационных методов лечения, которые будут приобретать все большее значение в современной медицине. Однако необходимо проводить дальнейшие исследования для более полного понимания механизмов действия магнитного поля на костную ткань и определения оптимальных параметров его применения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>magnetic field</kwd><kwd>bone tissue</kwd><kwd>regeneration</kwd><kwd>magnetotherapy</kwd><kwd>pulsed electromagnetic fields</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>магнитное поле</kwd><kwd>костная ткань</kwd><kwd>регенерация</kwd><kwd>магнитотерапия</kwd><kwd>импульсивные электромагнитные поля</kwd></kwd-group><funding-group><funding-statement xml:lang="en">This work was supported by the Russian Science Foundation grant no. 20–64–47008 (under affiliation of the Faculty of Biology, Lomonosov Moscow State University).</funding-statement><funding-statement xml:lang="ru">Работа выполнена при финансовой поддержке гранта РНФ № 20–64–47008 (по аффилиации Биологического факультета Московского государственного университета им. М.В. 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