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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3700</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Fractional flow reserve in definition for futher endovascular intervention in «false» bifurcation coronary lesions</article-title><trans-title-group xml:lang="ru"><trans-title>Роль фракционного резерва кровотока в определении тактики рентгенохирургического вмешательства при стентировании «ложных» бифуркационных стенозов коронарных артерий</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Movsesyants</surname><given-names>M U</given-names></name><name xml:lang="ru"><surname>Мовсесянц</surname><given-names>М Ю</given-names></name></name-alternatives><bio xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</bio><bio xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ivanov</surname><given-names>V A</given-names></name><name xml:lang="ru"><surname>Иванов</surname><given-names>В А</given-names></name></name-alternatives><bio xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</bio><bio xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Trunin</surname><given-names>I V</given-names></name><name xml:lang="ru"><surname>Трунин</surname><given-names>И В</given-names></name></name-alternatives><bio xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</bio><bio xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ivanov</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Иванов</surname><given-names>А В</given-names></name></name-alternatives><bio xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</bio><bio xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bobkov</surname><given-names>U A</given-names></name><name xml:lang="ru"><surname>Бобков</surname><given-names>Ю А</given-names></name></name-alternatives><bio xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</bio><bio xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Terekhin</surname><given-names>S A</given-names></name><name xml:lang="ru"><surname>Терехин</surname><given-names>С А</given-names></name></name-alternatives><bio xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</bio><bio xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mayskov</surname><given-names>V V</given-names></name><name xml:lang="ru"><surname>Майсков</surname><given-names>В В</given-names></name></name-alternatives><bio xml:lang="en">Кафедра госпитальной хирургииМедицинский факультет; Российский университет дружбы народов; Peoples' Friendship University of Russia</bio><bio xml:lang="ru">Кафедра госпитальной хирургииМедицинский факультет; Российский университет дружбы народов</bio><email>-</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Central Military Clinical Hospital № 3 after A.A. Vishnevsky</institution></aff><aff><institution xml:lang="ru">ФГУ «3 ЦВКГ им. А.А. Вишневского МО РФ»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Peoples' Friendship University of Russia</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2009-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2009</year></pub-date><issue>2</issue><issue-title xml:lang="en">NO2 (2009)</issue-title><issue-title xml:lang="ru">№2 (2009)</issue-title><fpage>26</fpage><lpage>31</lpage><history><date date-type="received" iso-8601-date="2016-09-07"><day>07</day><month>09</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="ru">Copyright ©; 2009, Мовсесянц М.Ю., Иванов В.А., Трунин И.В., Иванов А.В., Бобков Ю.А., Терехин С.А., Майсков В.В.</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Мовсесянц М.Ю., Иванов В.А., Трунин И.В., Иванов А.В., Бобков Ю.А., Терехин С.А., Майсков В.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/3700">https://journals.rudn.ru/medicine/article/view/3700</self-uri><abstract xml:lang="en">Main vessel stenting in the «false» bifurcation coronary lesions compromises side branch vessel ostium often. Functional significance of the side vessel ostium narrowing after main vessel stenting was defined in 40 patients with II-III classes of stable angina pectoris with isolated «false» bifurcation coronary lesions by means of a fractional flow reserve (FFR). Average side branch vessel ostium narrowing was 69,8 ± 8,7%, average value of FFR was detected 0,83 ± 0,06. It was noted, that the visual estimation and the quantitative coronary angiography are unreliable methods in assessment of the severity of side branch vessel ostium narrowing. The results of our study demonstrate, that if FFR &gt; 0,75 it is out of any benefit to conduct additional kissing balloon angioplasty of side brahch vessel ostium. Moreover, it was associated with high risk of side branch vessel dissection and ischemic myocardium injury.
            </abstract><trans-abstract xml:lang="ru">Стентирование магистральных артерий «ложных» бифуркационных стенозов коронарных артерий часто осложняется компрометацией устья боковой ветви. У 40 больных со стабильным течением стенокардии II-III ФК с изолированным «ложным» бифуркационным стенозом с помощью фракционного резерва кровотока (ФРК) была определена функциональная значимость сужения устья боковой ветви после стентирования магистальной артерии. При средней степени сужения устьев боковых ветвей на 69,8 ± 8,7%, средняя величина ФРК составила 0,83 ± 0,06. Установлено, что визуальная оценка и количественная коронарная ангиография являются ненадежными методами при оценке функциональной значимости компрометации устьев боковых ветвей. Полученные результаты свидетельствуют, что при величине ФРК &gt; 0,75 проведение дополнительной баллонной ангиопластики в устьях скомпрометированных боковых ветвей не улучшает отдаленный прогноз, в то время как ассоциируется с увеличением риска диссекции интимы боковых ветвей и ишемическим повреждением миокарда.
            </trans-abstract><kwd-group xml:lang="en"><kwd>bifurcation coronary lesions</kwd><kwd>fractional flow reserve (FFR)</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>бифуркационное стентирование</kwd><kwd>фракционный резерв кровотока (ФРК)</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Aliabadi D., Tilli F.V., Bowers T.R. et al. Incidence and angiographic predictors of side branch occlusion following high-pressure intracoronary stenting // Am. J. Cardiol. - 1997. - V. 80. - № 8. - P. 994-997.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Bon-Kwon Koo, Hyun-Jai Kang, Tae-Jin Youn et al. Physiologic Assessment of Jailed Side Branch Lesions Using Fractional Flow Reserve // J Am Coll Cardiol. - 2005. - V. 46. - P. 633-637.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Medina A., Surez de Lezo J., Pan M. A new classification of coronary bifurcation lesions // Rev. Esp. Cardiol. - 2006. - V. 59. - № 2. - P. 183-184.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Pijls N.H.J., De Bruyne B., Peels K. et al. Measurement of fractional flow reserve to assess the functional severity of coronary artery stenosis // N Engl J Med. - 1996. - V. 334. - P. 1703-1708.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Pijls N.H.J., van Schaardenburgh P., Manoharan G. et al. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study // -----J Am Coll Cardiol.  2007.  V. 49.  № 21.  P. 21052111 &lt;http://www.medscape.com/medline/publicationbrowser/123?pmid=17531660&gt;.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Tanabe K., Hole A., Lemos P.A. et al. Restenosis rates following bifurcation stenting with sirolimus-eluting stents for de novo narrowings // Am О Cardiol. - 2004. - V. 91. - P. 115-118.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Topol E.J., Nissen S.E. Our preoccupation coronary luminology: the dissociation between clinical and angiographic findings in ischemic heart disease // Circulation. - 1995. - V. 92.  - P. 2333-2342.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Wilson R.F., White C.W. Intracoronary papaverine: An ideal coronary vasodilator for studies of the coronary circulation in conscious humans // Circulation. - 1986. - V. 73. - P. 444-451.</mixed-citation></ref></ref-list></back></article>
