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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">35100</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2023-27-2-228-245</article-id><article-id pub-id-type="edn">FVUUDA</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>SURGERY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Evaluation of the efficiency of the expert medical decision making system in diagnosis acute appendicitis</article-title><trans-title-group xml:lang="ru"><trans-title>Оценка эффективности экспертной системы принятия врачебных решений в диагностике острого аппендицита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3427-4483</contrib-id><contrib-id contrib-id-type="spin">7831-2673</contrib-id><name-alternatives><name xml:lang="en"><surname>Burnevich</surname><given-names>Slavomir Z.</given-names></name><name xml:lang="ru"><surname>Бурневич</surname><given-names>С. З.</given-names></name></name-alternatives><email>burnslavomir@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-4034-8767</contrib-id><name-alternatives><name xml:lang="en"><surname>Maslenko</surname><given-names>Nikita S.</given-names></name><name xml:lang="ru"><surname>Масленко</surname><given-names>Н. С.</given-names></name></name-alternatives><email>burnslavomir@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">City Clinical Hospital named after V.V. Vinogradov</institution></aff><aff><institution xml:lang="ru">Городская клиническая больница имени В.В. Виноградова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-06-29" publication-format="electronic"><day>29</day><month>06</month><year>2023</year></pub-date><volume>27</volume><issue>2</issue><issue-title xml:lang="en">CARDIOVASCULAR DISEASES</issue-title><issue-title xml:lang="ru">ЗАБОЛЕВАНИЯ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ</issue-title><fpage>228</fpage><lpage>245</lpage><history><date date-type="received" iso-8601-date="2023-06-29"><day>29</day><month>06</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Burnevich S.Z., Maslenko N.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Бурневич С.З., Масленко Н.С.</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Burnevich S.Z., Maslenko N.S.</copyright-holder><copyright-holder xml:lang="ru">Бурневич С.З., Масленко Н.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/35100">https://journals.rudn.ru/medicine/article/view/35100</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Relevance. Timely diagnosis is the basic criterion for the quality of medical care in emergency department. One of the promising directions in the prevention of diagnostic errors is the use in clinical practice of the expert decision support system (EDSS). The aim of this study was a comparative analysis of the diagnostic efficiency of EDSS in acute appendicitis (AA) at various stages of the differential diagnosis of acute abdominal pain (AAP). Materials and methods. The study performed a retrospective analysis of the diagnostic results of 150 patients with various forms of AA, followed by the processing of structured clinical, laboratory and instrumental data using the original version of EDSS. Results and Discussion. It has been established that EDSS unidirectionally and sequentially models the stages of a standard diagnostic program for examining a patient with AAP at all levels of automated assessment of symptoms and signs of AA. Depending on the final parameters of the indication, the EDSS makes it possible to differentiate the variants of AA clinical scenarios with the identification of categories of diagnostic complexity that occurred in surgical practice. The data of relevance and validity of EDSS in the differential diagnosis of AAP are presented. The role of the expert system for the intensification of the doctor’s clinical reasoning and the prevention of diagnostic errors in emergency abdominal surgery is noted. Conclusion. The data obtained indicate a comparable diagnostic efficiency of the proposed version of EDSS with the accuracy of the diagnosis of a surgeon. The results of the preclinical use of EDSS allow the clinician to recommend its use in the format of an interactive “cognitive assistant” in case of possible difficulties and doubts in the differential diagnosis of AAP.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Актуальность. В отделениях неотложной хирургии своевременная диагностика является базовым критерием качественного оказания медицинской помощи. Одним из перспективных направлений в предупреждении диагностических ошибок рассматривается применение в клинической практике экспертных систем поддержки принятия врачебных решений (ЭСППВР). Целью настоящего исследования является сравнительное изучение диагностической эффективности ЭСППВР при остром аппендиците (ОА) на различных этапах дифференциальной диагностики острых заболеваний органов брюшной полости (ОЗОБП). Материалы и методы. В исследовании выполнен ретроспективный анализ результатов диагностики 150 пациентов с различными формами ОА с последующей обработкой структурированных клинических, лабораторных и инструментальных данных с помощью оригинальной версии ЭСППВР. Результаты и обсуждения. Установлено, что на всех уровнях автоматизированной оценки симптомов и признаков ОА ЭСППВР однонаправленно и последовательно моделирует этапы стандартной диагностической программы обследования пациента с болями в животе. В зависимости от итоговых параметров индикации ЭСППВР позволяет дифференцировать варианты клинических проявлений ОА с идентификацией категорий сложности диагностики, имевшей место в хирургической практике. Приводятся данные релевантности и валидности ЭСППВР при дифференциальной диагностике ОЗОБП. Отмечается роль экспертной системы для интенсификации клинических рассуждений врача и предупреждения диагностических ошибок в неотложной абдоминальной хирургии. Выводы. Полученные данные свидетельствуют о сравнимой диагностической эффективности предлагаемой версии ЭСППВР с точностью диагностики врача-хирурга. Результаты доклинического использования ЭСППВР позволяют рекомендовать клиницисту ее применение в формате интерактивного «когнитивного помощника» при возможных затруднениях и сомнениях в дифференциальной диагностике ОЗОБП.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute appendicitis</kwd><kwd>emergency abdominal surgery</kwd><kwd>diagnostic error</kwd><kwd>clinical reasoning</kwd><kwd>symptom checker</kwd><kwd>medical decision support system</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острый аппендицит</kwd><kwd>неотложная абдоминальная хирургия</kwd><kwd>диагностическая ошибка</kwd><kwd>клинические рассуждения</kwd><kwd>средство проверки симптомов</kwd><kwd>система поддержки принятия врачебных решений</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Rodziewicz TL, Houseman B, Hipskind JE. Medical Error Reduction and Prevention. [Updated 2022 Dec 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499956/</mixed-citation><mixed-citation xml:lang="ru">Rodziewicz T.L., Houseman B., Hipskind J.E. Medical error reduction and prevention // 2021. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2021.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Graber ML. The incidence of diagnostic error in medicine. BMJ Qual Saf. 2013;22 Suppl 2: ii21-ii27. doi: 10.1136/bmjqs-2012–001615.</mixed-citation><mixed-citation xml:lang="ru">Graber M.L. The incidence of diagnostic error in medicine // BMJ Qual Saf. 2013. Oct. 22 Suppl. 2: ii21-ii27. doi: 10.1136/bmjqs-2012-001615.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Eames J, Eisenman A, Schuster RJ. Disagreement between emergency department admission diagnosis and hospital discharge diagnosis: mortality and morbidity. Diagnosis (Berl). 2016;3(1):23–30. doi: 10.1515/dx-2015–0028.</mixed-citation><mixed-citation xml:lang="ru">Eames J., Eisenman A., Schuster R.J. Disagreement between emergency department admission diagnosis and hospital discharge diagnosis: mortality and morbidity // Diagnosis (Berl). 2016. V. 3. № 1. P. 23-30. doi: 10.1515/dx-2015-0028.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Newman-­Toker DE, Peterson SM, Badihian S, Hassoon A, Nassery N, Parizadeh D. et al. Diagnostic errors in the emergency department: a systematic review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US). 2022 Dec. Report No.: 22(23)-EHC043.</mixed-citation><mixed-citation xml:lang="ru">Newman-­Toker D.E., Peterson S.M., Badihian S., Hassoon A., Nassery N., Parizadeh D. et al. Diagnostic errors in the emergency department: a systematic review [Internet] // Rockville (MD): Agency for Healthcare Research and Quality (US). 2022. Dec. Report No: 22(23)-EHC043.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Holstine JB, Samora JB. Reducing surgical specimen errors through multidisciplinary quality improvement. Jt Comm J Qual Patient Saf. 2021 Sep;47(9):563–571. doi: 10.1016/j.jcjq.2021.04.003.</mixed-citation><mixed-citation xml:lang="ru">Holstine J.B., Samora J.B. Reducing surgical specimen errors through multidisciplinary quality improvement // Jt Comm J Qual Patient Saf. 2021. Sep. 47(9):563-571. doi: 10.1016/j.jcjq.2021.04.003.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Pan HM, Li HL, Shen ZS, Guo H, Zhao Q, Li JG. Observation of the effectiveness of a diagnostic model for acute abdominal pain based on the etiology checklist and process thinking. Risk Manag Healthc Policy. 2021;14:835–845. doi: 10.2147/RMHP.S295142.</mixed-citation><mixed-citation xml:lang="ru">Pan H.M., Li H.L., Shen Z.S., Guo H., Zhao Q., Li J.G. Observation of the effectiveness of a diagnostic model for acute abdominal pain based on the etiology checklist and process thinking // Risk Manag Healthc Policy. 2021. V. 14. P. 835-845. doi: 10.2147/RMHP.S295142.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Bokemeyer A, Ochs K, Fuhrmann V. Akutes abdomen: diagnostik [Acute abdomen: diagnostic management]. Dtsch Med Wochenschr. 2020;145(21):1544–1551. German. doi: 10.1055/a–1007–4264.</mixed-citation><mixed-citation xml:lang="ru">Bokemeyer A., Ochs K., Fuhrmann V. Akutes Abdomen: Diagnostik [Acute abdomen: diagnostic management] // Dtsch Med Wochenschr. 2020. V. 145. № 21. P. 1544-1551. German. doi: 10.1055/a-1007-4264.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Savelyev. V.S. Guidelines for emergency surgery of the abdominal organs: A guide for doctors. MIA. 2014. 544 p. [In Russian].</mixed-citation><mixed-citation xml:lang="ru">Cавельев В.С. Руководство по неотложной хирургии органов брюшной полости: Руководство для врачей. Москва: Изд-во МИА. 2014. С. 544.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Harada T, Watari T, Watanuki S, Hiroshige J, Kushiro S, Miyagami T. et al. Diagnostic error rates and associated factors for lower gastrointestinal perforation. Sci. Rep. 2022;12(1):1028. doi: 10.1038/s41598–021–04762-y.</mixed-citation><mixed-citation xml:lang="ru">Harada T., Watari T., Watanuki S., Hiroshige J., Kushiro S., Miyagami T. et al. Diagnostic error rates and associated factors for lower gastrointestinal perforation // Sci. Rep. 2022. V. 12. № 1. P. 1028. doi: 10.1038/s41598-021-04762-y.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Sutton RT, Pincock D, Baumgart DC, Sadowski DC, Fedorak RN, Kroeker KI. An overview of clinical decision support systems: benefits, risks, and strategies for success. NPJ Digit Med. 2020;3:17. doi: 10.1038/s41746–020–0221-y.</mixed-citation><mixed-citation xml:lang="ru">Sutton R.T., Pincock D., Baumgart D.C., Sadowski D.C., Fedorak R.N., Kroeker K.I. An overview of clinical decision support systems: benefits, risks, and strategies for success // NPJ Digit Med. 2020. V. 3. P. 17. doi: 10.1038/s41746-020-0221-y.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Faqar-­Uz-­Zaman SF, Anantharajah L, Baumartz P, Sobotta P, Filmann N, Zmuc D, von Wagner M, Detemble C, Sliwinski S, Marschall U, Bechstein WO, Schnitzbauer AA. The Diagnostic Efficacy of an App-based Diagnostic Health Care Application in the Emergency Room: eRadaR-Trial. A prospective, Double-­blinded, Observational Study. Ann Surg. 2022;276(5):935–942. doi: 10.1097/SLA.0000000000005614.</mixed-citation><mixed-citation xml:lang="ru">Faqar-­Uz-­Zaman S.F., Anantharajah L., Baumartz P., Sobotta P., Filmann N., Zmuc D. et al. The diagnostic efficacy of an app-based diagnostic health care application in the emergency room: eRadaR-Trial. A prospective, double-­blinded, observational study // Ann Surg. 2022. V. 276. № 5. P. 935-942. doi: 10.1097/SLA.0000000000005614.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Gowda NR, Kumar A, Arya SK, H V. The information imperative: to study the impact of informational discontinuity on clinical decision making among doctors. BMC Med Inform Decis Mak. 2020;20(1):175. doi: 10.1186/s12911–020–01190–2.</mixed-citation><mixed-citation xml:lang="ru">Gowda N.R., Kumar A., Arya S.K., Vikas H. The information imperative: to study the impact of informational discontinuity on clinical decision making among doctors // BMC Med Inform Decis Mak. 2020. V. 20. № 1. P. 175. doi: 10.1186/s12911-020-01190-2.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Wallace W, Chan C, Chidambaram S, Hanna L, Iqbal FM, Acharya A, Normahani P, Ashrafian H, Markar SR, Sounderajah V, Darzi A. The diagnostic and triage accuracy of digital and online symptom checker tools: a systematic review. NPJ Digit Med. 2022;5(1):118. doi: 10.1038/s41746–022–00667-w.</mixed-citation><mixed-citation xml:lang="ru">Wallace W., Chan C., Chidambaram S., Hanna L., Iqbal F.M., Acharya A., et al. The diagnostic and triage accuracy of digital and online symptom checker tools: a systematic review // NPJ Digit Med. 2022. V. 5. № 1. P. 118. doi: 10.1038/s41746-022-00667-w.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Baker A, Perov Y, Middleton K, Baxter J, Mullarkey D, Sangar D, Butt M, DoRosario A, Johri S. A Comparison of Artificial Intelligence and Human Doctors for the Purpose of Triage and Diagnosis. Front Artif Intell. 2020;3:543405. doi: 10.3389/frai.2020.543405.</mixed-citation><mixed-citation xml:lang="ru">Baker A., Perov Y., Middleton K., Baxter J., Mullarkey D., Sangar D. et al. A Comparison of artificial intelligence and human doctors for the purpose of triage and diagnosis. Front Artif Intell // 2020. V. 3. P.:543405. doi: 10.3389/frai.2020.543405.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">Burnevich S.Z., Soloviev D.A., Orlov B.B., Vatsik-­Gorodetskaya M.V., Nikolaev A.P., Filimonov M.I. Evaluation of the effectiveness of an expert diagnostic system in acute disorders of the mesenteric circulation. Physician and information technology. 2021;4:46–57. doi: 10.25881/18110193_2021_4_46. [In Russian].</mixed-citation><mixed-citation xml:lang="ru">Бурневич С.З., Соловьев Д.А., Орлов Б.Б., Вацик-­Городецкая М.В., Николаев А.П., Филимонов М.И. Оценка эффективности экспертной диагностической системы при остром нарушении мезентериального кровообращения // Врач и информационные технологии. 2021. № 4. С. 46-57. doi: 10.25881/18110193_2021_4_46.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">National clinical guidelines. Acute appendicitis in adults. Moscow. 2020. 45 p. [In Russian].</mixed-citation><mixed-citation xml:lang="ru">Острый аппендицит у взрослых // Национальные клинические рекомендации. 2020. Москва. 45 с.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">Mahajan P, Basu T, Pai CW, Singh H, Petersen N, Bellolio MF, Gadepalli SK, Kamdar NS. Factors Associated With Potentially Missed Diagnosis of Appendicitis in the Emergency Department. JAMA Netw Open. 2020;3(3): e200612. doi: 10.1001/jamanetworkopen.2020.0612.</mixed-citation><mixed-citation xml:lang="ru">Mahajan P., Basu T., Pai C.W., Singh H., Petersen N., Bellolio M.F. et al. Factors associated with potentially missed diagnosis of appendicitis in the emergency department // JAMA Netw Open. 2020. V. 3. № 3. P.: e200612. doi: 10.1001/jamanetworkopen.2020.0612.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">Sauter TC, Capaldo G, Hoffmann M, Birrenbach T, Hautz SC, Kämmer JE, Exadaktylos AK, Hautz WE. Non-specific complaints at emergency department presentation result in unclear diagnoses and lengthened hospitalization: a prospective observational study. Scand J Trauma Resusc Emerg Med. 2018;26(1):60. doi: 10.1186/s13049–018–0526-x.</mixed-citation><mixed-citation xml:lang="ru">Sauter T.C., Capaldo G., Hoffmann M., Birrenbach T., Hautz S.C., Kämmer J.E. et al. Non-specific complaints at emergency department presentation result in unclear diagnoses and lengthened hospitalization: a prospective observational study // Scand J Trauma Resusc Emerg Med. 2018. V. 26. № 1. P. 60. doi: 10.1186/s13049-018-0526-x.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">Norman GR, Monteiro SD, Sherbino J, Ilgen JS, Schmidt HG, Mamede S. The causes of errors in clinical reasoning: cognitive biases, knowledge deficits, and dual process thinking. Acad Med. 2017; 92(1):23–30. doi: 10.1097/ACM.0000000000001421.</mixed-citation><mixed-citation xml:lang="ru">Norman G.R., Monteiro S.D., Sherbino J., Ilgen J.S., Schmidt H.G., Mamede S. The causes of errors in clinical reasoning: cognitive biases, knowledge deficits, and dual process thinking // Acad Med. 2017. V. 92. № 1. P. 23-30. doi: 10.1097/ACM.0000000000001421.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">Schmidt HG, Mamede S. Improving diagnostic decision support through deliberate reflection: a proposal. Diagnosis (Berl). 2022;10(1):38–42. doi: 10.1515/dx-2022–0062.</mixed-citation><mixed-citation xml:lang="ru">Schmidt H.G., Mamede S. Improving diagnostic decision support through deliberate reflection: a proposal. // Diagnosis (Berl). 2022. V. 10. № 1. P. 38-42. doi: 10.1515/dx-2022-0062.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">Pelaccia T, Forestier G, Wemmert C. Deconstructing the diagnostic reasoning of human versus artificial intelligence. CMAJ. 2019;191(48): E1332-E1335. doi: 10.1503/cmaj.190506.</mixed-citation><mixed-citation xml:lang="ru">Pelaccia T., Forestier G., Wemmert C. Deconstructing the diagnostic reasoning of human versus artificial intelligence // CMAJ. 2019. V. 191. № 48. P. E1332-E1335. doi: 10.1503/cmaj.190506.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
