<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3423</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Risk factor of recurrent fetal growth with restiction</article-title><trans-title-group xml:lang="ru"><trans-title>Факторы риска повторных случаев задержки роста плода</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikolaeva</surname><given-names>M G</given-names></name><name xml:lang="ru"><surname>Николаева</surname><given-names>Мария Геннадьевна</given-names></name></name-alternatives><bio xml:lang="en">Department of obstetrics and gynecology № 2</bio><bio xml:lang="ru">Кафедра акушерства и гинекологии № 2</bio><email>nikolmg@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Altai State Medical University</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО АГМУ Минздрава РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2013</year></pub-date><issue>S5</issue><issue-title xml:lang="en">NOS5 (2013)</issue-title><issue-title xml:lang="ru">№S5 (2013)</issue-title><fpage>22</fpage><lpage>27</lpage><history><date date-type="received" iso-8601-date="2016-09-07"><day>07</day><month>09</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="ru">Copyright ©; 2013, Николаева М.Г.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Николаева М.Г.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/3423">https://journals.rudn.ru/medicine/article/view/3423</self-uri><abstract xml:lang="en">The case-control study was designed to determine prevalence and risk factors of fetal growth restriction (FGR) in 588 women. Two hundred fifty three factors were analyzed. It’s shown, that FGR history 6.1-fold increases the risk of FGR in consecutive pregnancy (OR 6.1; CI 95% 3.7—10.0; p &lt; 0.001). Main FGR risk factors are obesity (OR 7.6; CI 95% 2.0—29.2; p = 0.037), more than two cases of early pregnancy loss in history (OR 3.2; CI 95% 1.9—9.2; p = 0.037), chronic endometritis (OR 4.1; CI 95% 1.6—10.6; p = 0.006).</abstract><trans-abstract xml:lang="ru">Для установления факторов риска формирования повторных случаев задержки роста плода (ЗРП) проведено исследование «случай-контроль», в которое включено 588 женщин. Суммарное количество изученных факторов — 253. Показано, что факт ЗРП в анамнезе увеличивает риск формирования ЗРП в последующие беременности в 6,1 раз (ОШ 6,1; 95%ДИ 3,7—10,0; p = 0,006*10                  –11). Основными факторами риска повторных случаев ЗРП явились ожирение (ОШ 7,6; 95%ДИ 2,0—29,2; p = 0,019), наличие в анамнезе более 2 случаев самопроизвольных выкидышей (ОШ 5,4; 95%ДИ 1,4—21,0; p = 0,037) или неразвивающихся беременностей (ОШ 3,2; 95%ДИ 1,9—9,2; p = 0,034), хронический эндометрит (ОШ 4,1; 95%ДИ 1,6—10,6; p = 0,006).</trans-abstract><kwd-group xml:lang="en"><kwd>fetal growth restriction</kwd><kwd>risk factors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>задержка роста плода</kwd><kwd>факторы риска</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Cristiane Ortigosa Rocha, Roberto Eduardo Bittar, Marcelo Zugaib. Neonatal Outcomes of Late-Preterm Birth Associated or Not with Intrauterine Growth Restriction // Obstet. Gynec. Int. — 2010. — 2010: 231842.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Fomina M.P., Divakova T.S., Hotetovskaia G.V., Leonovich E.G. Particular cytokine status of amniotic fluid and umbilical blood in fetal growth delay syndrome // Bulletin of Peoples’ Friendship University of Russia. Series “Medicine. Obstetrics and Gynecology”. — 2012. — № 5. — P. 69—76.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Grinevich V.N. Gestational restructuring of spiral arteries in the utero-placental region in the first trimester of pregnancy when the placenta immaturity: dissertation of the PhD. — М., 2011. P. 27.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Ismailov S.I., Urmanova Yu.M., Mavlanov U.H., Khodjaeva F.S. To the factors influencing the normal growth of the fetus in the antenatal period // International Journal of Endocrinology. — 2011. — No. 4 (36).</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Kazantseva E.V., Dokgushina N.V. Modern aspects of pathogenesis, diagnosis and tactics of pregnant women with fetal growth delay syndrome // ENI Zabaykalsky medical bulletin. — 2012. — № 2. — P. 170—177.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Mook-Kanamori D.O. Risk factors and outcomes associated with first-trimester fetal growth restriction // JAMA. — 2010. — Feb 10. — № 303(6). — P. 527—34.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Nagaeva E.V. Fetal growth retardation // Pediatrics. — 2009. — T. 88, № 5. — P. 140—146.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Obstetrics: national leadership. Quick Start Guide / ed. A.C. Ajlamazian, V.N. Serov, V.E. Radzinsky, G.M. Savelyeva. — М.: GEOTAR-media, 2012.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Pulver LS, Guest-WarnickG, Stoddard GJ, et al. Weight for gestational age affects the mortality of late preterm infants // Pediatrics. — 2009. — 123 (6). — P. 1072—1077.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Radzinskiy V.E., Ordianc I.M., Orazmuradov A.A. Women’s consultation. — 3-ed. — М.: GEOTAR-media, 2009.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Reproductive health: Stud. posob. Ed. V.E. Radzinsky. — М.: RUDN, 2011.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Trishkin A.G. Reserves reducing perinatal mortality in the industrial region (by the example of the Kemerovo region): // dissertation of the MhD. — 2012. — P. 44.</mixed-citation></ref></ref-list></back></article>
