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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3422</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Indicators endointoxication and kidney function in pregnant women with portal hypertension</article-title><trans-title-group xml:lang="ru"><trans-title>Показатели эндогенной интоксикации и функция почек у беременных с портальной гипертензией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Britvina</surname><given-names>K V</given-names></name><name xml:lang="ru"><surname>Бритвина</surname><given-names>Ксения Владимировна</given-names></name></name-alternatives><bio xml:lang="en">Department of obstetrics and gynecology</bio><bio xml:lang="ru">Кафедра акушерства и гинекологии</bio><email>ksi09@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vasilyeva</surname><given-names>Z V</given-names></name><name xml:lang="ru"><surname>Васильева</surname><given-names>Зоя Васильевна</given-names></name></name-alternatives><bio xml:lang="en">Department of obstetrics and gynecology</bio><bio xml:lang="ru">Кафедра акушерства и гинекологии</bio><email>-</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kitsenko</surname><given-names>E A</given-names></name><name xml:lang="ru"><surname>Киценко</surname><given-names>Евгений Александрович</given-names></name></name-alternatives><bio xml:lang="en">Department of Emergency Surgery and portal hypertension</bio><bio xml:lang="ru">Отделение экстренной хирургии и портальной гипертензии</bio><email>kitsenko-surgeon@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mitichkin</surname><given-names>A E</given-names></name><name xml:lang="ru"><surname>Митичкин</surname><given-names>Александр Евгеньевич</given-names></name></name-alternatives><bio xml:lang="en">Moscow Department of Public Health</bio><email>nfo@gkb36.mosgorzdrav.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Apresyan</surname><given-names>S V</given-names></name><name xml:lang="ru"><surname>Апресян</surname><given-names>Сергей Владиславович</given-names></name></name-alternatives><bio xml:lang="en">The Department of Obstetrics and Gynecology with course of Perinatology Faculty of Medicine</bio><bio xml:lang="ru">Кафедра акушерства и гинекологии с курсом перинатологии Медицинский факультет</bio><email>sapresyan@mail.ru</email><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State Classical Academy Maimonides</institution></aff><aff><institution xml:lang="ru">Государственная классическая академия имени Маймонида</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Scientific Center Surgery Academician BV PetrovskyRussian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">ГУ РНЦХ им. академика Б.В. Петровского РАМН</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Municipal Clinical Hospital No 36</institution></aff><aff><institution xml:lang="ru">ГБУЗ Городская клиническая больница № 36 ДЗМ</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Peoples’ Friendship University of Russia</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2013</year></pub-date><issue>S5</issue><issue-title xml:lang="en">NOS5 (2013)</issue-title><issue-title xml:lang="ru">№S5 (2013)</issue-title><fpage>16</fpage><lpage>21</lpage><history><date date-type="received" iso-8601-date="2016-09-07"><day>07</day><month>09</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="ru">Copyright ©; 2013, Бритвина К.В., Васильева З.В., Киценко Е.А., Митичкин А.Е., Апресян С.В.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Бритвина К.В., Васильева З.В., Киценко Е.А., Митичкин А.Е., Апресян С.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/3422">https://journals.rudn.ru/medicine/article/view/3422</self-uri><abstract xml:lang="en">This article discusses the results of studies azotovydelitelnoy and filtration function of the kidneys, as well as indicators of endogenous intoxication in pregnant women with portal hypertension and baby on the content of middle molecules in the blood, urine and amniotic fluid.</abstract><trans-abstract xml:lang="ru">В данной статье рассматриваются результаты исследований азотовыделительной и фильтрационной функции почек, а также показателей эндогенной интоксикации у беременных с портальной гипертензией и новорожденных по содержанию среднемолекулярных пептидов в крови, моче и околоплодных водах.</trans-abstract><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>portal hypertension</kwd><kwd>endogenous intoxication</kwd><kwd>middle peptides</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>портальная гипертензия</kwd><kwd>эндогенная интоксикация</kwd><kwd>среднемолекулярные пептиды</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Apresyan S.V. 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