RUDN Journal of MedicineRUDN Journal of Medicine2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)3345Review ArticleEpigenetics and epigenetic mechanisms in myomaEseneevaF Meseneeva85@bk.ruKiselevV Ivkis10@mail.ruSalimovaL Yleilasal@mail.ruPeoples’ Friendship University of RussiaResearch division of early carcinogenesis, prevention, diagnosis and complex treatment of oncological diseases of the female reproductive organs fsbi “Russian scientific center of radiology”V.M. Buyanov City Clinical Hospital15022016216017007092016Copyright © 2016,2016This article is about main modern aspects of pathogenesis of myoma, including epigenetics. The authors made an attempt to demonstrate the most investigated epigenetic mechanisms, perspectives of their researching and possible application in practice.myomaepigeneticsepigenetic mechanismsDNA methylationHistone modificationMicro RNAEpigenetic therapyмиома маткиэпигенетикаэпигенетические механизмыДНК-метилированиемодификация гистонов«замалчивание» микро-РНКэпигенетическая терапия