RUDN Journal of MedicineRUDN Journal of MedicineВестник Российского университета дружбы народов. Серия: Медицина2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)3339ArticlesСтатьиReview ArticleImmunologic aspects of pathogenesis of endometrial diseaseИммунологические аспекты патогенеза эндометриоидной болезниBabayevaE IБабаеваЭльвира Ильхамовнаelvira-3333@mail.ruAryutinD GАрютинДмитрий Геннадьевичarutin@mail.ruNovginovD SНовгиновДмитрий Сергеевичnovginov@mail.ruPeoples’ Friendship University of RussiaРоссийский университет дружбы народов150220162NO2 (2016)№2 (2016)12312607092016Copyright ©; 2016, Бабаева Э.И., Арютин Д.Г., Новгинов Д.С.2016Бабаева Э.И., Арютин Д.Г., Новгинов Д.С.http://creativecommons.org/licenses/by/4.0https://journals.rudn.ru/medicine/article/view/3339Endometrioid disease (ED) is multifactorial nature of etiopathogenesis. Since the control of hemostasis in human tissue provided by the immune system, it is clear that the basis of violations of the timely elimination of the altered cells are the body's immunological disorders. Consequently, the basis of endometriosis should lie immune disorders. The article is devoted to the currently existing problems and controversial issues in relation to the pathogenesis of external genital endometriosis. The review presents the national and international research, as well as its own approach to the problem, the prospects and possible solutions.Эндометриоидная болезнь (ЭБ) носит мультифакторный характер этиопатогенеза. Поскольку контроль тканевого гемостаза у человека обеспечивается иммунной системой, представляется очевидным, что в основе нарушений своевременной элиминации измененных клеток из организма лежат иммунологические нарушения. Следовательно, в основе эндометриоза должны лежать иммунные нарушения. Статья посвящена существующим в настоящее время проблемам и спорным вопросам в отношении патогенеза наружного генитального эндометриоза. В обзоре представлены данные отечественных и зарубежных исследований, а также собственный взгляд на проблему, перспективы и возможные пути ее решения.external genital endometriosisendometrial diseasereproductive healthнаружный генитальный эндометриозэндометриоидная болезньрепродуктивное здоровье1.Adamyan L.V., Zaratianc O.V., Maksimova Yu.V. et al. Proliferative activity of ektopic and eutopic of the endometrium at various locations of endometriosis: what's new? New technologies in diagnosis and treatment of gynecological diseases. 2010. P. 150-151.2.Adamyan L.V., Andreyeva E.N. Role of modern hormone modulating therapy in complex treatment of genital endometriosis. Reproduction Problems. 2011. No. 6. P. 66-77.3.Barri P.N., Coroleu B., Tur R. et al. Endometriosis-associated infertility: surgery and IVF, a comprehensive therapeutic approach. Reprod. 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