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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3336</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The prevention of development of sharp pulmonary damage in patients with the severe combined injury</article-title><trans-title-group xml:lang="ru"><trans-title>Предупреждение развития острого легочного повреждения у больных с тяжелой сочетанной травмой</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tyurin</surname><given-names>I N</given-names></name><name xml:lang="ru"><surname>Тюрин</surname><given-names>Игорь Николаевич</given-names></name></name-alternatives><email>tyurin.dti@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rautbart</surname><given-names>S A</given-names></name><name xml:lang="ru"><surname>Раутбарт</surname><given-names>Сергей Александрович</given-names></name></name-alternatives><email>raut2s@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shurygin</surname><given-names>S N</given-names></name><name xml:lang="ru"><surname>Шурыгин</surname><given-names>Сергей Николаевич</given-names></name></name-alternatives><email>gkb12@zdrav.mos.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Salikov</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Саликов</surname><given-names>Александр Викторович</given-names></name></name-alternatives><email>gkb12@zdrav.mos.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State budgetary healthcare institution “City clinical hospital named V.M. Buyanova”</institution></aff><aff><institution xml:lang="ru">Государственное бюджетное учреждение здравоохранения «Городская клиническая больница имени В.М. Буянова» Департамента здравоохранения города Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2016</year></pub-date><issue>2</issue><issue-title xml:lang="en">NO2 (2016)</issue-title><issue-title xml:lang="ru">№2 (2016)</issue-title><fpage>103</fpage><lpage>109</lpage><history><date date-type="received" iso-8601-date="2016-09-07"><day>07</day><month>09</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="ru">Copyright ©; 2016, Тюрин И.Н., Раутбарт С.А., Шурыгин С.Н., Саликов А.В.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Тюрин И.Н., Раутбарт С.А., Шурыгин С.Н., Саликов А.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/3336">https://journals.rudn.ru/medicine/article/view/3336</self-uri><abstract xml:lang="en">The retrospective analysis of clinical records of 25 patients with the severe combined injury for the purpose of an assessment of influence of changes of volemichesky support on development of sharp injury of lungs is made. Monitoring of haemo dynamics and the volemichesky status carried out by means of technology of the modified PiCCO plus termodilyution (Pulsion Medical Systems, Germany). During the analysis it was revealed that application of haemo dynamic monitoring with use of a transpulmonalny termodilyution and the PiCCO technology, allows to improve authentically oxygenation index indicators, to reduce duration of respiratory support and a ball assessment of weight of a condition of patients, on an integrated scale of SOFA. From this it is possible to draw a conclusion that application of volemichesky monitoring of PiCCO allows to prevent development of the sharp injury of lungs (SIL) in patients with the severe combined injury.</abstract><trans-abstract xml:lang="ru">Выполнен ретроспективный анализ историй болезни 25 пациентов с тяжелой сочетанной травмой с целью оценки влияния изменений волемической поддержки на развитие острого повреждения легких. Мониторинг гемодинамики и волемического статуса выполняли с помощью технологии модифицированной термодилюции PiCCO plus (Pulsion Medical Systems, Германия). В ходе анализа было выявлено, что применение гемодинамического мониторинга с использованием транспульмональной термодилюции и технологии PiCCO позволяет достоверно улучшить показатели индекса оксигенации, снизить длительность респираторной поддержки и бальную оценку тяжести состояния больных, по интегральной шкале SOFA. Из этого можно сделать вывод, что применение волемического мониторинга PiCCO позволяет предотвратить развитие острого повреждения легких (ОПЛ) у больных тяжелой сочетанной травмой (ТСТ).</trans-abstract><kwd-group xml:lang="en"><kwd>severe combined injury</kwd><kwd>transpulmonalny termodilyution</kwd><kwd>volemichesky support</kwd><kwd>oxygenation index</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>тяжелая сочетанная травма</kwd><kwd>транспульмональная термодилюция</kwd><kwd>волемическая поддержка</kwd><kwd>индекс оксигенации</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Gelfand B.R., Saltanov A.I. Intensive Therapy. National Guide. 2009. Vol. P. 183-197.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Grigoriev E.G., Apartsyn K.A., Kornilov N.G. et al. Epidemiology concomitant injury in the industrial centers of Eastern Siberia. Bulletin VSCN SO RAMN. 2005. No. 3. 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