RUDN Journal of MedicineRUDN Journal of Medicine2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)3333Research ArticleRational pharmacotherapy of uterine fibroids in their reproductive yearsGalinaT Vtatyana.galina1@mail.ruStykinY Ostikyar@inbox.ruErmolovaN Pstikyar@inbox.ruGolikovaT Pnaramm@mail.ruPeoples’ Friendship University of Russia150220162879107092016Copyright © 2016,2016The article presents comparative research data to improve the reproductive health of women with uterine fibroids with antiprogestins, selective progesterone receptor modulators (SPRM) and gonadotropin-releasing hormone (GnRH), depending on the size, location and clinical manifestations of leiomyoma. To evaluate the effectiveness of therapy was carried out clinical and statistical analysis of the survey results in patients with uterine myoma patients and analyzed the results of laboratory and instrumental methods of examination in dynamics during treatment and for 6 months after graduation.uterine fibroidsantiprogestinsSPRMGnRHмиома маткиантипрогестиныСМРПаГнРГ