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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">32997</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2022-26-4-441-450</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Physiology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Физиология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Association between maximal aerobic capacity and heart rate variability</article-title><trans-title-group xml:lang="ru"><trans-title>Связь между максимальной аэробной способностью и вариабельностью сердечного ритма</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8154-9385</contrib-id><name-alternatives><name xml:lang="en"><surname>Saini</surname><given-names>Ravi</given-names></name><name xml:lang="ru"><surname>Шайни</surname><given-names>Р.</given-names></name></name-alternatives><email>sainiravi414@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6505-4216</contrib-id><name-alternatives><name xml:lang="en"><surname>Kacker</surname><given-names>Sudhanshu</given-names></name><name xml:lang="ru"><surname>Какер</surname><given-names>С.</given-names></name></name-alternatives><email>sainiravi414@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5932-6764</contrib-id><name-alternatives><name xml:lang="en"><surname>Gupta</surname><given-names>Reshu</given-names></name><name xml:lang="ru"><surname>Гупта</surname><given-names>Р.</given-names></name></name-alternatives><email>sainiravi414@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0343-5777</contrib-id><name-alternatives><name xml:lang="en"><surname>Rao</surname><given-names>Aayushee</given-names></name><name xml:lang="ru"><surname>Рао</surname><given-names>А.</given-names></name></name-alternatives><email>sainiravi414@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">RUHS College of medical sciences</institution></aff><aff><institution xml:lang="ru">RUHS Колледж медицинских наук</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-12-23" publication-format="electronic"><day>23</day><month>12</month><year>2022</year></pub-date><volume>26</volume><issue>4</issue><issue-title xml:lang="en">GINECOLOGY</issue-title><issue-title xml:lang="ru">ГИНЕКОЛОГИЯ</issue-title><fpage>441</fpage><lpage>450</lpage><history><date date-type="received" iso-8601-date="2022-12-23"><day>23</day><month>12</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Saini R., Kacker S., Gupta R., Rao A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Шайни Р., Какер С., Гупта Р., Рао А.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Saini R., Kacker S., Gupta R., Rao A.</copyright-holder><copyright-holder xml:lang="ru">Шайни Р., Какер С., Гупта Р., Рао А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/32997">https://journals.rudn.ru/medicine/article/view/32997</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Relevance. Сardiovascular status could be assessed by maximal aerobic capacity (VO2max) through direct analysis of the gases involved in pulmonary ventilation and monitoring fluctuations in intervals between beats over time as heart rate variability. The aim of the study was to investigate the relationship between VO<sub>2</sub>max and heart rate variability in young adults. Materials and Methods. A total of 100 young adults between the ages of 18 and 25 were included in observational study, who did not engage in any strenuous physical activity, 50 of whom were male and 50 of whom were female.There were measured Heart rate variability in the frequency domain; LF, HF, LF/HF, and time domain; SDNN, RMSSD, pNN 50, and VO<sub>2</sub>max were assessed using a treadmill test according to Graded Exercise Protocol. Results and Discussion. There was weak positive correlation of VO2max with LF ( r = 0.177) and weak negative correlation with HF ( r = -0.141). Male participants had a weak negative relationship between VO2 max and LF ( r = -0.075), whereas female respondents had a weak positive relationship(r = 0.286). There was weak negative correlation of VO<sub>2</sub>max with LF/HF ratio for male subjects but weak positive correlation ( r = -0.101) for female subjects. For male and female participants, there was a weak negative association of VO2max with SDNN ( r = -0.170) and ( r = -0.301), respectively. Male and female participants had a weak negative association of VO<sub>2</sub>max  with RMSSD, with ( r = -0.154) and ( r = -0.284) respectively. Male and female participants had a slight negative association of VO<sub>2</sub>max with pNN 50, with ( r = -0.062) and ( r = -0.441) respectively. Conclusion. Significant variations were found in the time domain and frequency domain indices including HF and LF/HF ratio which represents the balance between sympathetic and parasympathetic responses.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Актуальность. Сердечно-сосудистый статус можно оценить по максимальной аэробной емкости (VO2max) путем прямого анализа газов, участвующих в легочной вентиляции и наблюдения за колебаниями интервалов между сокращениями во времени как вариабельностью сердечного ритма. Целью исследования было изучение взаимосвязи между VO<sub>2</sub>max и вариабельностью сердечного ритма у молодых людей. Материалы и методы . В обсервационное исследование было включено 100 молодых людей в возрасте от 18 до 25 лет, которые не занимались какой-либо тяжелой физической деятельностью, 50 из которых были мужчинами и 50 женщинами. Измерялась вариабельность сердечного ритма в частотной области; НЧ, ВЧ, НЧ/ВЧ и временная область; SDNN, RMSSD, pNN 50 и VO2max оценивали с помощью теста на беговой дорожке в соответствии с протоколом поэтапных упражнений. Результаты и обсуждение . Отмечена слабая положительная корреляция VO<sub>2</sub>max с LF ( r = 0,177) и слабая отрицательная корреляция с HF ( r = -0,141). У участников мужского пола была слабая отрицательная связь между VO<sub>2</sub>max и LF ( r = -0,075), тогда как у респондентов женского пола была слабая положительная связь ( r = 0,286). Отрицательная корреляция VO<sub>2</sub>max с соотношением LF/HF была слабой у мужчин и слабой положительной корреляцией ( r = -0,101) у женщин. Для участников мужского и женского пола наблюдалась слабая отрицательная связь VO<sub>2</sub>max с SDNN ( r = -0,170) и ( r = -0,301) соответственно. Участники мужского и женского пола имели слабую отрицательную связь VO<sub>2</sub>max с RMSSD, с ( r = -0,154) и ( r = -0,284) соответственно. У участников мужского и женского пола была небольшая отрицательная связь VO<sub>2</sub>max с pNN 50 с ( r = -0,062) и ( r = -0,441) соответственно. Вывод. Значительные вариации были обнаружены во временной и частотной областях, включая HF и отношение LF/HF, которое представляет собой баланс между симпатическими и парасимпатическими ответами.</p></trans-abstract><kwd-group xml:lang="en"><kwd>frequency domain</kwd><kwd>graded exercise protocol</kwd><kwd>heart rate variability</kwd><kwd>time domain</kwd><kwd>VOmax</kwd><kwd>VOmax</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>частотная область</kwd><kwd>поэтапный протокол упражнений</kwd><kwd>вариабельность сердечного ритма</kwd><kwd>временная область</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Shephard RJ, Allen C, Benade AJ, Davies CT, Di Prampero PE, Merriman JE, Myhre K, Simmons R. The maximum oxygen intake. An international reference standard of cardio respiratory fitness. 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