RUDN Journal of MedicineRUDN Journal of Medicine2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)3153Research ArticleDigital Tomosynthesis in Diagnosis of impalpable Breast CancerGrinbergM VDeparment of Oncology and Rentgenoradiology; Russian Scientific Center of Roentgenoradiology (FGBOU RSCRR) of Ministry of Health of Russian Federation.drmgrinberg@gmail.comHarchenkoN VDeparment of Oncology and Rentgenoradiology; Russian Scientific Center of Roentgenoradiology (FGBOU RSCRR) of Ministry of Health of Russian Federation.nharchenko@gmail.comKundaM ADeparment of Oncology and Rentgenoradiology; Russian Scientific Center of Roentgenoradiology (FGBOU RSCRR) of Ministry of Health of Russian Federation.mkunda@mail.ruZapirovM MDeparment of Oncology and Rentgenoradiology; Russian Scientific Center of Roentgenoradiology (FGBOU RSCRR) of Ministry of Health of Russian Federation.zapirov@mail.ruRozhkovaN Inadezhda@gmail.comPeoples’ Friendship University of RussiaMoscow Oncology Institute n.a. Hertsen (FMRC) of Ministry of Health of Russian Federation150320153466007092016Copyright © 2015,2015Purpose . To compare the diagnostic performance of digital breast tomosynthesis (DBT) and digital mammography (DM) for breast cancers. Materials and Methods . The study included fifty-seven patients with histologically verified breast cancer. Given the subjective evaluation of the benefits of technology for tomosynthesis imaging of pathological signs characteristic of breast cancer (tumour, focal asymmetry, restructuring or microcalcifications). The data obtained on the base of DM and additional DBT information were assessed according to BI-RADS scale (force BI-RADS). The interdependence between the categories according to BI-RADS scale and the nature of the radiological manifestations of breast cancer was determined using Chi-square (c 2) test. Results . A total of 59 breast cancers were reviewed, including 17 (28.8%) mass lesions, 12 (20.3%) focal asymmetry/density, 6 (10.2%) restructuring, 23 (39.0%) calcifications, and 1 (1.7%) intracystic tumor. Mammography with DBT was more informative to visualize 58.8% of the lesions, 83,3% of focal asymmetry, 94.4% of violations architectonics and only 11.6% of the signs of microcalcifications. When making conclusion on BI-RADS scale, in 84.4% of cases category of findings was increased from 0 (when performing DM) to 4 or 5 (when performing DBT). Category opinions 4A on the scale of BI-RADS in the implementation of DM in 27.3% of cases was increased after evaluation of the images of the DBT, a symptom of malignancy in this category were mainly detected microcalcifications. Significant interdependence ( p 0,001) between BI-RADS category and pathological radiographic signs was noted. Conclusion . DBT allows to obtain more accurate visual information about mass formation, focal asymmetry, violation of the architectonics and improves the diagnostic efficacy of mammography.gynecologyradiation doseimpalpable massesimage interpretationradiation exposuremammographybreast X-raya series of imagescomparative analysissuperposition of tissue structuresmicrocalcificationstomosynthesisгинекологиядозовая нагрузканепальпируемые образованияинтерпретация изображениялучевая нагрузкамаммографиямолочная железарентгеновский аппаратсерия снимковсравнительный анализсуперпозиция тканевых структурмикрокальцинатытомосинтез