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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">27538</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2021-25-3-219-228</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>SOCIAL HEALTH AND HEALTH PROTECTION</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ ЗДРАВООХРАНЕНИЯ И ОБЩЕСТВЕННОЕ ЗДОРОВЬЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Analysis of the epidemiological characteristics and risk factors for epilepsy in the countries of the African continent</article-title><trans-title-group xml:lang="ru"><trans-title>Анализ эпидемиологических особенностей и факторов риска эпилепсии в странах Африканского континента</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9134-3049</contrib-id><name-alternatives><name xml:lang="en"><surname>Efremov</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Ефремов</surname><given-names>В. В.</given-names></name></name-alternatives><email>jk161@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5351-2419</contrib-id><name-alternatives><name xml:lang="en"><surname>Dolgusheva</surname><given-names>Yu. A.</given-names></name><name xml:lang="ru"><surname>Долгушева</surname><given-names>Ю. А.</given-names></name></name-alternatives><email>jk161@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2588-4570</contrib-id><name-alternatives><name xml:lang="en"><surname>Ndihokubvayo</surname><given-names>B.</given-names></name><name xml:lang="ru"><surname>Ндихокубвайо</surname><given-names>Б.</given-names></name></name-alternatives><email>jk161@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov State Medical University</institution></aff><aff><institution xml:lang="ru">Ростовский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-10-02" publication-format="electronic"><day>02</day><month>10</month><year>2021</year></pub-date><volume>25</volume><issue>3</issue><issue-title xml:lang="en">PULMONOLOGY</issue-title><issue-title xml:lang="ru">ПУЛЬМОНОЛОГИЯ</issue-title><fpage>219</fpage><lpage>228</lpage><history><date date-type="received" iso-8601-date="2021-10-02"><day>02</day><month>10</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Efremov V.V., Dolgusheva Y.A., Ndihokubvayo B.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Ефремов В.В., Долгушева Ю.А., Ндихокубвайо Б.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Efremov V.V., Dolgusheva Y.A., Ndihokubvayo B.</copyright-holder><copyright-holder xml:lang="ru">Ефремов В.В., Долгушева Ю.А., Ндихокубвайо Б.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/27538">https://journals.rudn.ru/medicine/article/view/27538</self-uri><abstract xml:lang="en"><p style="text-align: justify;">Relevance . Epilepsy is a common neurological disease in tropical countries, especially in Africa. Its prevalence in African countries is almost twice as high as in Asia, Europe and North America. Objective: to investigate the characteristics of the spread and risk factors of epilepsy in the countries of the African continent. Materials and Methods : Based on WHO data, an epidemiological analysis of the prevalence and structure of mortality from epilepsy among the inhabitants of continental Africa was carried out. The African continent was clustered into five different regions with conventionally homogeneous sociocultural, climatic and geographic and environmental conditions and, as a consequence, similar dynamics of endemic diseases and infections. Demographic data, etiological factors, risk factors such as infectious diseases (including neglected diseases) with neurological consequences in the form of deaths from epilepsy were compared in five centers in the region. Mathematical and statistical processing of the results was carried out using the SPSS-19 statistical package (SPSS Inc., USA). Results and Discussion . Analysis of socio-demographic characteristics made it possible to establish that mortality from epilepsy is higher: in the countries of the African continent south of the Sahara in comparison with northern Africa; in women compared to men; in the age group younger than 14 compared to older groups and also in countries of subregions with an unsatisfactory state of national health systems and a low level of socio-economic situation in general. Conclusion . State programs aimed at reducing various factors of injury, violence, the prevalence of maternal mortality and hunger, the frequency of suicide among the population can help reduce the prevalence and mortality from epilepsy. In addition, a significant number of risk factors for epilepsy in African countries are virulent and potentially preventable. First of all, these include: neurocysticercosis, schistosomiasis, HIV infection and various forms of meningitis. Health care interventions to prevent these diseases can also significantly reduce the prevalence of epilepsy.</p></abstract><trans-abstract xml:lang="ru"><p style="text-align: justify;">Актуальность . Эпилепсия является распространенным неврологическим заболеванием в тропических странах, особенно в странах Африки. Ее распространенность в африканских странах почти вдвое выше, чем в Азии, Европе и Северной Америке. Цель: провести исследование и дать интерпретацию особенностям распространения и факторам риска эпилепсии в странах Африканского континента. Материалы и методы . Основываясь на данных ВОЗ, проведен эпидемиологический анализ распространенности и структуры смертности от эпилепсии среди жителей континентальной Африки. Африканский континент был кластеризирован на пять различных регионов с условно однородными социально-культурными, климатогеографическими и средовыми условиями и, как следствие, схожей динамикой эндемических заболеваний и инфекций. Далее, в пяти центрах этого региона были сопоставлены демографические данные, этиологические факторы, факторы риска, такие как инфекционные заболевания с неврологическими последствиями в виде смертельных случаев от эпилепсии. Математико-статистическая обработка результатов проведена с помощью статистического пакета SPSS-19 (SPSS Inc., USA). Результаты и обсуждение . Анализ социально-демографических характеристик позволил установить, что смертность от эпилепсии выше: в странах Африканского континента к югу от Сахары по сравнению с северной Африкой; у женщин по сравнению с мужчинами; в возрастной группе моложе 14 лет по сравнению со старшими группами; а также в странах субрегионов с неудовлетворительным состоянием национальных систем здравоохранения и низким уровнем социально-экономической ситуации в целом. Выводы . Государственные программы, направленные на снижение различных факторов травматизма, насилия, распространенности материнской смертности и голода, частоты суицида среди населения могут способствовать снижению распространенности и смертности от эпилепсии. Кроме того, существенный объем факторов риска эпилепсии в странах Африки является вирулентным и потенциально-предотвратимым. Прежде всего к ним относятся: нейроцистицеркоз, шистосомоз, ВИЧ-инфекция и различные формы менингита. Мероприятия в системе здравоохранения, ориентированные на профилактику этих заболеваний, также могут существенно снизить распространенность эпилепсии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>neurology</kwd><kwd>epilepsy</kwd><kwd>evidence-based medicine</kwd><kwd>continental Africa</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>неврология</kwd><kwd>эпилепсия</kwd><kwd>доказательная медицина</kwd><kwd>континентальная Африка</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Standard country or area codes for statistical use (M49). https://unstats.un.org/unsd/methodology/m49/. (Accessed January 20, 2021)</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Global Health Observatory data repository (WHO). https://apps.who.int/gho/data/node.home. 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