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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">RUDN Journal of Medicine</journal-id><journal-title-group><journal-title xml:lang="en">RUDN Journal of Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник Российского университета дружбы народов. Серия: Медицина</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-0245</issn><issn publication-format="electronic">2313-0261</issn><publisher><publisher-name xml:lang="en">Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">22521</article-id><article-id pub-id-type="doi">10.22363/2313-0245-2019-23-3-328-334</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Epidemiology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Эпидемиология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Mathematical Modelling and Prediction in Infectious Disease Epidemiology</article-title><trans-title-group xml:lang="ru"><trans-title>Математическое моделирование и прогнозирование в эпидемиологии инфекционных заболеваний</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yanchevskaya</surname><given-names>E. Ya.</given-names></name><name xml:lang="ru"><surname>Янчевская</surname><given-names>Е. Ю.</given-names></name></name-alternatives><email>apteca-111a@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mesnyankina</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Меснянкина</surname><given-names>О. А.</given-names></name></name-alternatives><email>apteca-111a@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Astrakhan State Medical University</institution></aff><aff><institution xml:lang="ru">Астраханский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2019</year></pub-date><volume>23</volume><issue>3</issue><issue-title xml:lang="en">VOL 23, NO3 (2019)</issue-title><issue-title xml:lang="ru">ТОМ 23, №3 (2019)</issue-title><fpage>328</fpage><lpage>334</lpage><history><date date-type="received" iso-8601-date="2019-12-24"><day>24</day><month>12</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Yanchevskaya E.Y., Mesnyankina O.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Янчевская Е.Ю., Меснянкина О.А.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Yanchevskaya E.Y., Mesnyankina O.A.</copyright-holder><copyright-holder xml:lang="ru">Янчевская Е.Ю., Меснянкина О.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/medicine/article/view/22521">https://journals.rudn.ru/medicine/article/view/22521</self-uri><abstract xml:lang="en"><p>Mathematical modeling of diseases is an urgent problem in the modern world. More and more researchers are turning to mathematical models to predict a particular disease, as they help the most correct and accurate study of changes in certain processes occurring in society. Mathematical modeling is indispensable in certain areas of medicine, where real experiments are impossible or difficult, for example, in epidemiology. The article is devoted to the historical aspects of studying the possibilities of mathematical modeling in medicine. The review demonstrates the main stages of development, achievements and prospects of this direction.</p></abstract><trans-abstract xml:lang="ru"><p>Математическое моделирование заболеваний является актуальной проблемой в современном мире. Все больше исследователей обращаются к математическим моделям для составления прогноза того или иного заболевания, так как они помогают наиболее правильно и точно изучить изменения определенных процессов, происходящих в социуме. Математическое моделирование незаменимо в определенных областях медицины, где невозможны или затруднены реальные эксперименты, например в эпидемиологии. Статья посвящена историческим аспектам изучения возможностей применения математического моделирования в медицине. Обзор демонстрирует основные этапы развития, достижения и перспективы данного направления.</p></trans-abstract><kwd-group xml:lang="en"><kwd>mathematical modeling</kwd><kwd>forecasting</kwd><kwd>epidemiology</kwd><kwd>infectious diseases</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>математическое моделирование</kwd><kwd>прогнозирование</kwd><kwd>эпидемиология</kwd><kwd>инфекционные заболевания</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Uly`bin AV. A mathematical model of the spread of infection. Vestnik TGU. 2011. 16 (1): 184—187. (In Russ)</mixed-citation><mixed-citation xml:lang="ru">Улыбин А.В. 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