RUDN Journal of Medicine

Вестник Российского университета дружбы народов. Серия: Медицина

2313-02452313-0261

Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)

16642

10.22363/2313-0245-2017-21-2-219-226

Articles

Статьи

Research Article

PREDICTORS OF ADVERSE LEFT VENTRICULAR REMODELING IN PATIENTS AFTER MYOCARDIAL INFARCTION

ПРЕДИКТОРЫ НЕБЛАГОПРИЯТНОГО РЕМОДЕЛИРОВАНИЯ ЛЕВОГО ЖЕЛУДОЧКА У ПАЦИЕНТОВ, ПЕРЕНЕСШИХ ИНФАРКТ МИОКАРДА

Zharikova

E S

Жарикова

Е С

konovalov_oe@rudn.university

Villevalde

S V

Виллевальде

С В

konovalov_oe@rudn.university

Kobalava

Z D

Кобалава

Ж Д

зав. кафедрой кардиологии и клинической фармакологии ФПК МР РУДН

zkobalava@mail.ru

RUDN University, Moscow, RussiaРоссийский университет дружбы народов, Москва, Россия

15122017

212

VOL 21, NO2 (2017)

ТОМ 21, №2 (2017)

21922609092017

2017

Zharikova E.S., Villevalde S.V., Kobalava Z.D.

Жарикова Е.С., Виллевальде С.В., Кобалава Ж.Д.

http://creativecommons.org/licenses/by/4.0

https://journals.rudn.ru/medicine/article/view/16642

Functional recovery or irreversible negative remodeling of injured myocardial segments has different prognostic implication in patients with myocardial infarction (MI) undergoing coronary percutaneous intervention (PCI). Increased pulse wave velocity (PWV), a non-invasive index of arterial stiffness, is one of the important risk factors of cardiovascular events in different clinical conditions. The aim of the study was to assess the relationship between PWV and changes of left ventricular (LV) systolic function in patients with acute MI. Adverse cardiac remodeling was revealed in 72% of patients and they more often had non-recovery of left ventricular longitudinal function. Higher baseline PWV is associated with less effective recovery of LV function.

Функциональное восстановление или неблагоприятное ремоделирование поврежденных сегментов миокарда имеет разное прогностическое значение у пациентов с инфарктом миокарда (ИМ). Повышенная скорость пульсовой волны (СРПВ), оценка продольной деформации миокарда являются одними из важных факторов риска сердечно-сосудистых событий в различных клинических усло-виях. Целью исследования была оценка взаимосвязи между СРПВ и изменениями систолической функции левого желудочка у пациентов, перенесших острый ИМ. Установлено, что повышенная СРПВ и сниженная продольная глобальная деформация являются независимыми предикторами неблагоприятного ремоделирования левого желудочка.

myocardial infarctionarterial stiffnessadverse LV remodeling

инфаркт миокардаартериальная жесткостьнеблагоприятное ремоде-лирование ЛЖ

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