Research studies of probiotic acilact versions using animal models

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  • Authors: Pospelova VV1, Cherepanova Y.V1, Lahtin VM1, Krivoruchko EV1, Ulianova LP2, Gvozdik TE3, Arshba IM3
  • Affiliations:
    1. G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology
    2. Research Center for Medical Radiology of the Russian Academy of Medical Science
    3. Research Institute for Medical Primatology of the Russian Academy of Medical Science
  • Issue: No 1 (2009)
  • Pages: 5-10
  • Section: Articles
  • URL: http://journals.rudn.ru/medicine/article/view/3758
  • Cite item

Abstract


The effectiveness of different probiotic Acilact versions was investigated using animal models. The high protective activity of heat treated Acilact version was demonstrated in the experiments on mice which had suffered the combined radiation and thermic injuries. The effectiveness of medicinal cosmetic cream prepared from the Acilact supernatant was tested on rabbits and monkeys. The experiments on rabbits showed that the inflammatory foci caused by the intracutaneous injection of Staphylococcus culture were repaired more rapidly than in the control group. The cream had a positive impact on the burn and wound healing after traumatic injuries in monkeys.

About the authors

V V Pospelova

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

Yu V Cherepanova

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

V M Lahtin

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

E V Krivoruchko

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology

L P Ulianova

Research Center for Medical Radiology of the Russian Academy of Medical Science

Research Center for Medical Radiology of the Russian Academy of Medical Science

T E Gvozdik

Research Institute for Medical Primatology of the Russian Academy of Medical Science

Research Institute for Medical Primatology of the Russian Academy of Medical Science

I M Arshba

Research Institute for Medical Primatology of the Russian Academy of Medical Science

Research Institute for Medical Primatology of the Russian Academy of Medical Science

References

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Copyright (c) 2009 Поспелова В.В., Черепанова Ю.В., Лахтин В.М., Криворучко Е.В., Ульянова Л.П., Гвоздик Т.Е., Аршба И.М.

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