Correlation between cells blood aggregation and peripheral blood cells lymphocyte aberration in brain glioma patients

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  • Authors: Frolov VA1, Syatkin SP1, Fedoronchuk TV1, Gridina NY.2, Boltina IV3, Ushenin Y.V4
  • Affiliations:
    1. Peoples' Friendship University of Russia
    2. State Institution Institute of Neurosurgery NAMS of Ukraine
    3. L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine
    4. V.E. Lashkarev Institute of semiconducter physics NAS Ukraine
  • Issue: No 1 (2012)
  • Pages: 11-16
  • Section: Articles
  • URL: http://journals.rudn.ru/medicine/article/view/3295
  • Cite item

Abstract


The correlation between the peripheral blood cells aggregation level measured by surface plasmon resonance method (SPR), and chromosomal abberations of peripheral blood lymphocytes in brain malignant gliomas patients was investigated. It was found, that results of SPR in patients with brain gliomas were significantly lower than in healthy persons and gradually decreased with increasing of the gliomas malignancy grade. It was shown that decreasing of SPR data correlate with the statistically significant increase of chromosomal aberration in peripheral blood lymphocytes in glioma patients.

About the authors

V A Frolov

Peoples' Friendship University of Russia

Email: syata@mail.ru <mailto:syata@mail.ru>
Peoples' Friendship University of Russia

S P Syatkin

Peoples' Friendship University of Russia

Email: syata@mail.ru <mailto:syata@mail.ru>
Peoples' Friendship University of Russia

T V Fedoronchuk

Peoples' Friendship University of Russia

Email: syata@mail.ru <mailto:syata@mail.ru>
Peoples' Friendship University of Russia

N Ya Gridina

State Institution Institute of Neurosurgery NAMS of Ukraine

Email: syata@mail.ru <mailto:syata@mail.ru>
State Institution Institute of Neurosurgery NAMS of Ukraine

I V Boltina

L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine

Email: syata@mail.ru <mailto:syata@mail.ru>
L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine

Yu V Ushenin

V.E. Lashkarev Institute of semiconducter physics NAS Ukraine

Email: syata@mail.ru <mailto:syata@mail.ru>
V.E. Lashkarev Institute of semiconducter physics NAS Ukraine

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Copyright (c) 2012 Фролов В.А., Сяткин С.П., Федорончук Т.В., Гридина Н.Я., Болтина И.В., Ушенин Ю.В.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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