Exogenous serotonin potentiates vagal reaction of the colon

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Abstract


This study is dedicated to serotoninergic structures of the colon. Experiments were performed in 35 Chinchilla rabbits under general anesthesia, mechanical ventilation, bilateral vagotomy. Mechanical and electrical activity of the ascending colon was recorded during electrical stimulation of the peripheral part of the right n. vagi in intact animals and after serotonin adipate injection. It was found that serotonin potentiates vagal effects of the colon, but without effect on duration of reaction. Concluded that the serotoninergic structures of the colon are able to control the parasympathetic portion of the autonomic nervous system.

About the authors

V I Torshin

Peoples' Friendship University of Russia

Email: rudnvestnik@yandex.ru
Кафедра нормальной физиологииМедицинский факультет; Российский университет дружбы народов; Peoples' Friendship University of Russia

V M Smirnov

Russian State Medical University

Email: rudnvestnik@yandex.ru
Кафедра нормальной физиологии; Российский государственный медицинский университет; Russian State Medical University

D S Sveshnikov

Russian State Medical University

Email: rudnvestnik@yandex.ru
Кафедра нормальной физиологии; Российский государственный медицинский университет; Russian State Medical University

A V Kuchuk

Russian State Medical University

Email: rudnvestnik@yandex.ru
Кафедра нормальной физиологии; Российский государственный медицинский университет; Russian State Medical University

I L Myasnikov

Russian State Medical University

Email: rudnvestnik@yandex.ru
Кафедра нормальной физиологии; Российский государственный медицинский университет; Russian State Medical University

References

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Copyright (c) 2012 Торшин В.И., Смирнов В.М., Свешников Д.С., Кучук А.В., Мясников И.Л.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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