Effect of acute focal ischemia on the thermal balance of the brain

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Abstract

Heat balance of homoiothermic animals allows significant physiological deviation from the preset settings “set point” centers of hypothalamic regulation despite of the difficult-organised system of its maintenance. In other words, the warm-blooded organism normally has thermal heterogeneity. With the development of pathological states, accompanied by fever and increasing of body temperature, temperature heterogeneity is changing. The origin of these changes is rarely the subject of special studies, because the algorithm of the diagnosis is usually considered as an assessment of basal temperature in one department thermal “center” only. However, the increase of the temperature of the brain in patients with cerebral accidents does not always correspond to the changes in basal body temperature, which can lead to the underestimation of local hyperthermia of the brain in traditional thermomonitoring. Anatomical, functional and metabolic features create the special conditions of maintenance of the cerebral temperature balance in comparison with the conditions of regulation of temperature of the heat “center”.

About the authors

D V Cheboksarov

Peoples’ Friendship University of Russia

Email: dcheboksarov@gmail.com
Department of anesthesiology and resuscitation

O A Shevelev

Peoples’ Friendship University of Russia

Email: shevelev_o@mail.ru
Department of General pathology and pathological physiology

A V Butrov

Peoples’ Friendship University of Russia

Email: avbutrov@mail.ru
Department of anesthesiology and resuscitation

M A Buntina

Peoples’ Friendship University of Russia

Email: avbutrov@mail.ru
Department of anesthesiology and resuscitation

A V Shestov

RR neurosurgical Institute n.a. A.L. Polenov

Email: navygaradav@mail.ru

I L Privalova

Kursk state medical University

Email: shevelev_o@mail.ru
Physiology Laboratory Research Institute of environmental medicine

References


Copyright (c) 2014 Чебоксаров Д.В., Шевелев О.А., Бутров А.В., Бунтина М.А., Шестов А.В., Привалова И.Л.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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