Meningococcal polyvaccine on the basis of cleared IgAI protease

Cover Page
  • Authors: Alliluev A.P., Anohina I.V., Rumsh L.D., Kotelnikova O.V., Drozzina E.Y., Zhigis L.S., Yagudaeva E.Y., Razgulyaeva O.A., Zueva S.S., Kozlov L.V., Bichucher A.M., Avakov A.E.
  • Issue: No 1 (2010)
  • Pages: 7-12
  • Section: Articles
  • URL: http://journals.rudn.ru/medicine/article/view/2624

Abstract


IgA1-protease allocated from the culture N. meningitidis serogroup A. As original materials were used three different intermediate products of vaccine production: cultural fluid, cetavlon supernatant and cetavlon precipitate. IgA1-protease was used to evaluate their protectivity and immunogenity. It was shown, that isolated IgA1 protease from the meningococcus serogroup A is able to protect mice, infected by meningococcus serogroup B.

A P Alliluev

'Peoples Friendship University of Russia <http://www.multitran.ru/c/m.exe?t=4557871_1_2>

Email: alliluevap@mail.ru <mailto:alliluevap@mail.ru>
Кафедра микробиологииМедицинский факультет; Российский университет дружбы народов; 'Peoples Friendship University of Russia

I V Anohina

'Peoples Friendship University of Russia <http://www.multitran.ru/c/m.exe?t=4557871_1_2>

Кафедра микробиологииМедицинский факультет; Российский университет дружбы народов; 'Peoples Friendship University of Russia

L D Rumsh

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория химии протеолитических ферментов; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

O V Kotelnikova

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория химии протеолитических ферментов; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

E Yu Drozzina

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория химии протеолитических ферментов; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

L S Zhigis

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория полимеров для биологии; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

E Yu Yagudaeva

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория полимеров для биологии; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

O A Razgulyaeva

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория полимеров для биологии; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

S S Zueva

M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

Лаборатория полимеров для биологии; ИБХ им. ак. М.М. Шемякина и Ю.А. Овчинникова РАН; M.M. Shemyakin & Yu.A. Ovchinnikov Instituteof Bioorganic Chemistry, Russian Academy of Sciences

L V Kozlov

G.N. Gabrichevsky Moscow Research Instituteof Epidemiology and Microbiology of Russia

G.N. Gabrichevsky Moscow Research Instituteof Epidemiology and Microbiology of Russia

A M Bichucher

G.N. Gabrichevsky Moscow Research Instituteof Epidemiology and Microbiology of Russia

G.N. Gabrichevsky Moscow Research Instituteof Epidemiology and Microbiology of Russia

A E Avakov

The branch of the federal state unitary enterpriseResearch-and-production association «Microgene» G.N. GabrichevskyThe enterprise for manufacture bacterial preparations

The branch of the federal state unitary enterpriseResearch-and-production association «Microgene» G.N. GabrichevskyThe enterprise for manufacture bacterial preparations

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Copyright (c) 2010 Аллилуев А.П., Анохина И.В., Румш Л.Д., Котельникова О.В., Дрожжина Е.Ю., Жигис Л.С., Ягудаева Е.Ю., Разгуляева О.А., Зуева В.С., Козлов Л.В., Бичучер А.М., Аваков А.Э.

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