The effect of prednisolone on the NSE- and CD-68-positive cells of the spleen

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Abstract


The aim of our research was to study the effect of prednisolone on the quantitative and morphological characteristics of NSE+ and CD-68+ cells in different functional zones of the spleen. During the morphometrical research we set up five morphotypes of NSE+-cells and four morphotypes of CD-68+ cells. It showed that CD-68+ cells of II type and NSE+-cells (II and IV types) are more sensitive to prednisolone. We came to the conclusion that there is a probability of identity of subpopulations I NSE+ and 2 CD-68+, II NSE+ and 4 CD-68+, III NSE+ and 4 CD-68+ because they are characterised by identical morphological indicators in norm and in experiment.

E М Luzikova

Chuvash State University

Email: nema76@mail.ru <mailto:sdragon@mail.ru>
Кафедра медицинской биологии; ЧГУ; Chuvash State University

V E Sergeeva

Chuvash State University

Email: nema76@mail.ru <mailto:sdragon@mail.ru>
Кафедра медицинской биологии; ЧГУ; Chuvash State University

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Copyright (c) 2009 Лузикова Е.М., Сергеева В.Е.

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