Antidiphtheria immunity at children with allergic diseases

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Abstract


Levels of antitoxic and antibacterial antibodies against diphtheria were estimated at 151 children without vaccination and 152 vaccinated ones with DPT-vaccine and revaccinated children with ADT-M anatoxine (1-15 years) with allergic diseases (bronchial asthma, atopic dermatitis, pollynosis). State of antibacterial immunity not correlated with process of antidiphtheria medicines' vaccination, but depends on natural circulation of incinant. Risk group to diphtheria consisted of 1-6 years children, having the lowest level of antibacterial antibodies. Process of antidiphtherial antibacterial IgG formation is slower than antibacterial IgM and IgA formation and reaches their maximal level at 7-8 years, while IgM and Ig A - to 4-6 years.

A V Labushkina

Rostov state medical university

Email: somvoz@live.ru <mailto:somvoz@live.ru>
Кафедра микробиологии и вирусологии № 2; Ростовский государственный медицинский университет; Rostov state medical university

G G Kharseeva

Rostov state medical university

Email: somvoz@live.ru <mailto:somvoz@live.ru>
Кафедра микробиологии и вирусологии № 2; Ростовский государственный медицинский университет; Rostov state medical university

E P Moskalenko

Rostov state medical university

Email: somvoz@live.ru <mailto:somvoz@live.ru>
Кафедра микробиологии и вирусологии № 2; Ростовский государственный медицинский университет; Rostov state medical university

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Copyright (c) 2009 Лабушкина А.В., Харсеева Г.Г., Москаленко Е.П.

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