Influence opioids on oxidizing stress and sphingosine way of activation of apoptosis in kidneys

Abstract


It was established that dalarginum injection before AKF (acute kidney failure) formation prevented decrease of the contents sphingosine and fragmentations DNA, increas of SOD (superoxiddismutase) in the kidneys.
The probability of correlation connection between at the activation of sphingomyelin cycle and the state of antioxidant systems which can influence on the regulation of apoptosis is determined.

About the authors

Y A Belous

Peoples' Friendship University of Russia

Кафедра психотерапии и наркологии ФПКМР; Российский университет дружбы народов; Peoples' Friendship University of Russia

I A Komarevtseva

LGMU

Кафедра медицинской химии; ЛГМУ; LGMU

K V Komarevtseva

LGMU

Кафедра медицинской химии; ЛГМУ; LGMU

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Copyright (c) 2009 Белоус Ю.А., Комаревцева И.А., Комаревцева Е.В.

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