Effect of transplantation of fetal rabbit islets of langerhans to streptozotocin-indused diabetic mice

I K Abdrakhmanov; Абдрахманов Игорь Камильевич; N B Savenko; Савенко Наталья Борисовна; Yu A Kuznetsov; Кузнецов Юрий Алексеевич; M A Selyugin; Селюгин Максим Александрович; L P Dyakonov; Дьяконов Лев Петрович

Effect of transplantation of fetal rabbit islets of langerhans to streptozotocin-indused diabetic mice

Authors: Abdrakhmanov IK¹, Savenko NB², Kuznetsov Y.A³, Selyugin MA³, Dyakonov LP¹
Affiliations:
1. Russian People's Friendship University
2. JSC «Russian R&D Center of agriculture emergency»
3. Veterinary clinic «Avers-vet»
Issue: No 4 (2011)
Pages: 70-76
Section: Articles
URL: https://agrojournal.rudn.ru/agronomy/article/view/1343

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Abstract

This article is about the trial of transplantation of fetal cells of pancreas to laboratory mice with streptosotozin diabetes. Cells were infused into liver in the dose of 105 cells/0,5 ml. Mices that received rabbit β-cells had normal level blood glucose within 2 months after xenotransplantation.

Keywords

diabetes, xenotransplantation, beta cells, pancreatic islet cells, rabbit embryo, streptozotocin, laboratory mice

About the authors

I K Abdrakhmanov

Russian People's Friendship University

Email: abdrakhman@mail.ru
Кафедра анатомии, физиологии животных и хирургии; Российский университет дружбы народов; Russian People's Friendship University